Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

ArtWater

Financiado

The possibility of artificial life at subzero temperatures: the role of water in...

The possibility of artificial life at subzero temperatures: the role of water in cell-mimicking compartments In the last few decades, researchers have come to believe that where there is liquid water, there is life, regardless of the physical conditions of the surroundings. Indeed, living organisms have been discovered in environments wi... ver más

31/12/2028

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

UNIVERSITEIT UTRECHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-12-20

ERC-2022-STG: ERC STARTING GRANTS Scope:Objectives

I+D

Cerrada hace 2 años

0% 100% 100%

1 Participantes

1.75M€ | Lider

Proyectos interesantes

CGL2015-74254-JIN BUSQUEDA DE EVIDENCIAS MOLECULARES DE VIDA EN AMBIENTES EXTR... 203K€ Cerrado

PID2020-114047GB-I00 IMITANDO EL SUBSUELO PLANETARIO EN EL LABORATORIO 153K€ Cerrado

EvoTrap Mechanisms to emerge and replicate the first sequence infor... 2M€ Cerrado

FIS2009-12365 COMPUTACION. REPLICACION Y ROTURA DE SIMETRIA EN SISTEMAS PR... 90K€ Cerrado

ProIce Biological ice formation Probing the interplay between ice... 207K€ Cerrado

PID2020-113936GB-I00 QUIMICA INTERESTELAR RELEVANTE PARA EL ORIGEN DE LA VIDA 121K€ Cerrado

Últimas noticias

02-12-2024: AGENCIA-VALENCIANA-D... En las últimas 48 horas el Organismo AGENCIA VALENCIANA D... ha otorgado 1 concesiones

02-12-2024: CDTI En las últimas 48 horas el Organismo CDTI ha otorgado 4 concesiones

01-12-2024: REDES En las últimas 48 horas el Organismo REDES ha otorgado 1337 concesiones

Duración del proyecto: 72 meses Fecha Inicio: 2022-12-20
Fecha Fin: 2028-12-31

Líder del proyecto

UNIVERSITEIT UTRECHT

TRL 4-5

Presupuesto del proyecto 2M€

Descripción del proyecto In the last few decades, researchers have come to believe that where there is liquid water, there is life, regardless of the physical conditions of the surroundings. Indeed, living organisms have been discovered in environments with extreme temperatures, radiation, or high salinity. In terms of temperature, the lowest limit to sustain the metabolic activities of bacteria is reported to be -20 ºC in permafrost. Yet, the survival mechanism of life below the freezing point of water is still not fully understood, though it has important implications for origin of life studies and the search for life in the universe. The prerequisite of life at subzero temperatures is the existence of liquid water. Intracellular liquid water not only serves as solution medium, but also plays a crucial role in biological processes such as metabolisms in cells. Therefore, understanding the physical state of intracellular water at subzero temperatures is important. In ArtWater, we will employ synthetic compartments as model system to investigate the physical state of compartmentalized water at subzero temperatures. The project will be conducted through a bottom-up approach: from pure water in compartments to crowded compartmentalized solutions that mimic cytoplasm in natural cells. The crystallization, diffusion, and dynamics of water will be studied by differential scanning calorimetry, nuclear magnetic resonance, and broadband dielectric spectroscopy, respectively. Several types of state-of-the-art synthetic compartments will be employed including polymersomes, liposomes, and complex coacervates. Furthermore, we will develop artificial cells equipped with liquid water enabling biological activities at subzero temperatures. The ArtWater project will not only open the window for understanding the survival mechanisms at extremely low temperatures but also provide a new platform for tunable bioengineering processes such as cryopreservation and cryo-enzymology and shed light to astrobiology.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores