Innovating Works

Glial Patterning

Financiado
The genetic basis for glial differentiation in the developing zebrafish retina.
Glia far out number neurons in the brain and their defects are now known to be associated with many neurological diseases. Glial specification and physiological function are very well studied however, remarkably little is known ab... Glia far out number neurons in the brain and their defects are now known to be associated with many neurological diseases. Glial specification and physiological function are very well studied however, remarkably little is known about they way in which glia are positioned or shaped in order to perform their critical support functions. The goal of the present study is to broaden the field of glial development by using new techniques to ask previously unattainable questions. This central goal of this research project is carried out through an in-depth morphological, genetic and transcritpomic analyses of differentiating Müller Glia in the Zebrafish (Danio rerio) eye. Results from these studies will provide and the first extensive profiling of a differentiating glial population. Furthermore, the extensive data that will be generated in this proposal will provide a basis for many future studies on glial biology for both in the host laboratory and for the experienced researcher during his career development. Ultimately, these and future studies will provide a foundation for identifying the molecular networks that underlie glial patterning in the brain that will no doubt be informative in the study of glial related neurological disease. ver más
28/02/2018
THE CHANCELLOR MAS...
195K€
Duración del proyecto: 24 meses Fecha Inicio: 2016-02-24
Fecha Fin: 2018-02-28

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2018-02-28
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
MSCA-IF-2015-EF: Marie Skłodowska-Curie Individual Fellowships (IF-EF)
Cerrada hace 9 años
Presupuesto El presupuesto total del proyecto asciende a 195K€
Líder del proyecto
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UN... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5