Innovating Works

SIREM

Financiado
Systemic Induced Root Exudation of Metabolites A Multimodal Approach to Uncover...
Systemic Induced Root Exudation of Metabolites A Multimodal Approach to Uncover Root Signaling Mechanisms and the Chemical Language used by Plants to Shape the Rhizosphere Microbiome The prosperity of plants and human beings is dependent on the outer layer of soil that makes up our planet’s shell. Curiously, a significant portion of plants' most precious elements, carbon and nitrogen, is secreted by roots into... The prosperity of plants and human beings is dependent on the outer layer of soil that makes up our planet’s shell. Curiously, a significant portion of plants' most precious elements, carbon and nitrogen, is secreted by roots into soil in the form of chemically-rich exudates. This is not merely 'dumping' of waste but rather the chemical language of plants, used in their underground communication with billions of detrimental and beneficial microorganisms. Yet, an important question remains to date: How do plants control and manipulate root metabolism and exudation in time and space to fine-tune this complex underground web of interactions to their benefit? The proposed project takes on this challenging question and aims to decipher the newly discovered process we term 'SIREM', for 'Systemic Induced Root Exudation of Metabolites'. SIREM is a fundamental feature of rhizosphere interactions, in which biotic stimuli occur locally and exudation in systemic parts of the root ‘conditions’ the rhizosphere environment to maintain plant fitness. SIREM objectives include: (i) dissecting the SIREM signaling pathways, focusing primarily on the mobile signal(s) and receiving proteins at the systemic root; (ii) discovery of the exudation machinery and its genetic control; and (iii) establishing the role of SIREM signaling and exudation-metabolites in shaping the rhizosphere microbiome. The unconventional integration of approaches in SIREM underscores the unique combination of our team's expertise in plant metabolism, computational biology, microbiome exploration and the application of cutting-edge analytical and molecular technologies for high-resolution spatial-temporal profiling. Outcomes of the project will have wide-ranging impacts on understanding systemic signaling and metabolic and transport systems in plants and are anticipated to drive the new biotechnological concept of 'Exudation Agriculture'. ver más
30/04/2025
3M€
Duración del proyecto: 60 meses Fecha Inicio: 2020-04-22
Fecha Fin: 2025-04-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2020-04-22
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2019-ADG: ERC Advanced Grant
Cerrada hace 5 años
Presupuesto El presupuesto total del proyecto asciende a 3M€
Líder del proyecto
WEIZMANN INSTITUTE OF SCIENCE No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5