AAV-FACTORY
Financiado
Synthetic Viral Nanosystem for Highly Efficient AAV Manufacturing for Gene Thera...
Gene therapy is one of the most innovative and fastest growing fields in the pharmaceutical industry. The first approved gene therapy utilized a recombinant AAV vector (rAAV), and dozens of additional rAAVs for gene therapy are pr...
Gene therapy is one of the most innovative and fastest growing fields in the pharmaceutical industry. The first approved gene therapy utilized a recombinant AAV vector (rAAV), and dozens of additional rAAVs for gene therapy are presently in clinical trials. rAAV gene therapy drugs have been priced in the region of € 500’000 and above, which is partially a result of them being manufactured by highly complex processes combining multiple components, requiring 5-7 separate GMP production runs. We intend to introduce the first scalable, single-virus rAAV production platform to resolve this bottleneck. The resulting significant reduction of manufacturing complexity will both lower the price of future rAAV gene therapies, and also deliver additional, currently unaddressed or unaffordable rAAV treatments for genetic diseases into the clinic by providing scientists operating at the laboratory R&D stage with more user friendly and productive tools. The proposed project also develops for PoC purposes an rAAV gene therapy candidate to treat the devastating childhood congenital disease known as steroid resistant nephrotic syndrome SRNS.
ver más
Duración del proyecto: 26 meses
Fecha Inicio: 2020-11-16
Fecha Fin: 2023-01-31
Fecha Fin: 2023-01-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2023-01-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ERC-2020-POC:
Call for proposals for ERC Proof of Concept Grant
Cerrada
hace 4 años
Presupuesto
El presupuesto total del proyecto asciende a
150K€
Líder del proyecto
UNIVERSITY OF BRISTOL
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
336.95K€ |
Participante