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synBIOcarb

Financiado

Cerrado

Synthetic biology of carbohydrate binding proteins engineering protein carbohyd...

Synthetic biology of carbohydrate binding proteins engineering protein carbohydrate interactions for diagnostics and cell targeting The aim of the Initial Training Network will be to train 15 early stage researchers in the emerging field of synthetic glycobiology, equipping them with the skills needed for future careers in the medical technologies sector. Ever... ver más

31/03/2023

UNIVLEEDS

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

UNIVERSITY OF LEEDS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 15 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-03-31

MSCA-ITN-2018: Innovative Training Networks

I+D

Cerrada hace 7 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

15 Participantes

UNIVLEEDS

909.52K€ | Lider

N.D. | Participante

UORL

N.D. | Participante

enGenes

264.21K€ | Participante

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Duración del proyecto: 55 meses Fecha Inicio: 2018-08-20
Fecha Fin: 2023-03-31

Líder del proyecto

UNIVERSITY OF LEEDS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The aim of the Initial Training Network will be to train 15 early stage researchers in the emerging field of synthetic glycobiology, equipping them with the skills needed for future careers in the medical technologies sector. Every living cell is covered in a coating of complex carbohydrates known as the glycocalyx. Anything that approaches the cell membrane must first descend through this forest of carbohydrates. Interactions between carbohydrates and lectins (carbohydrate-binding proteins) play essential roles in cell adhesion and endocytosis. Our growing understanding of glycoscience, and the advent of chemical and synthetic biology methodologies, presents an opportunity to redesign, synthesise and exploit glycocalyx and lectin components for diverse analytical, diagnostic and targeted therapeutic applications: this is the field of Synthetic Glycobiology. The ESF-funded report, A Roadmap for Glycosicence in Europe, has highlighted the importance of glycoscience to the European bioeconomy. The European glycomics market is growing rapidly (>10% growth p.a.). There is an urgent need to train ESRs with the scientific and entrepreneurial skills required to enable European industry to exploit this rapidly growing market. The synBIOcarb ETN brings together a diverse team of chemists, structural biologists, biophysicists, cell biologists and protein engineers who are pioneering the development of Synthetic Glycobiology, and four SMEs that are leading industrial innovation in glycoscience and protein engineering. Together, we will train 15 ESRs in the essential enabling technologies that underpin the development and exploitation of glycoscience: glycoconjugate synthesis; lectin engineering; biophysical interaction measurements; cell biology; analytical device technologies; entrepreneurial and transferable skills.

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