Synaptic Dysfunction in Neuropsychiatric Disorders
The large public health burden and individual suffering associated with mental disorders speaks to the need to study their biological underpinning. Genetic research, animal models of disease and human neuroimaging studies have pro...
ver más
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Proyectos interesantes
BFU2015-71464-R
MECANISMOS FISIOPATOLOGICOS DE LA RUTA SINAPTICA DE NEUREXIN...
182K€
Cerrado
SYMBAD
Synapses from molecules to higher brain function and diseas...
5M€
Cerrado
COSYN
Comorbidity and Synapse Biology in Clinically Overlapping Ps...
6M€
Cerrado
NEURO-MIR-NETWORKS
MicroRNA Networks in Neuronal Development and Plasticity
100K€
Cerrado
CANDY
Comorbid Analysis of Neurodevelopmental Disorders and Epilep...
6M€
Cerrado
SynaNet
Neurologic and Psychiatric Disorders from synapses to netwo...
1,000K€
Cerrado
Información proyecto Syn2Psy
Duración del proyecto: 60 meses
Fecha Inicio: 2018-08-20
Fecha Fin: 2023-08-31
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
The large public health burden and individual suffering associated with mental disorders speaks to the need to study their biological underpinning. Genetic research, animal models of disease and human neuroimaging studies have provided convergent evidence to common pathways implicated in their aetiology, namely pathways that regulate synapse development and plasticity, which result in abnormal structural and functional connectivity in the brain of neuropsychiatric patients. The time has come to integrate studies across different levels, leading to the identification of signatures of illness associated to specific risk pathways, which can drive the development of novel therapies.
The objective of Syn2Psy is to provide high-level Ph.D. training for 14 early stage researchers (ESRs) to answer three critical questions: 1) What are the synaptic defects at the basis of neuropsychiatric disorders? 2) Which are the neuronal circuits that are disrupted, and may be targets for therapies? 3) How and when can we modulate the course of disease? Syn2Psy combines strong scientific with complementary know-how from the non-academic sector, and network-wide actions on scientific and complementary soft skills, to train a new generation of high achieving ESRs and provide them with the transferable skills necessary for thriving careers in a flourishing area. Industrial partners Lundbeck, Eurotrials and ZEISS provide experience on drug, clinical trials and technology development, the Coimbra University Hospital will expose the students to clinical research, while the clinic for child development PIN and the Marionet theatre company offer training in societal awareness and outreach. The excellent basic scientific knowledge and diverse skills acquired by ESRs will enhance their employment prospects in both the academic and non-academic sectors, and their scientific contributions will inform novel therapeutic approaches for alleviating this leading cause of disability worldwide.