Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SYMPHONY

Financiado

Cerrado

Sudden Cardiac Death and Electrical Dyssynchrony Mediated by Purkinje His Dysfun...

Sudden Cardiac Death and Electrical Dyssynchrony Mediated by Purkinje His Dysfunctional Activity Cardiovascular disease is the first cause of mortality in the whole world (WHO 2008), responsible for 700000 deaths each year in Europe; a huge burden on healtcare. Half of this mortality is due to heart failure (HF), which can be... ver más

31/08/2018

UBx

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

UNIVERSITE DE BORDEAUX No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2018-08-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

UBx

0.00€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

SMARTHEART Directed networks as a novel approach for improving the mana... 1M€ Cerrado

PSCD Establishing the role of Purkinje fibres in the development... 194K€ Cerrado

Optoheart All optical framework for the correlative imaging of cardiac... 213K€ Cerrado

NaV1.5-CARED NaV1.5 regulation fine-tuning as a therapy for cardiac Condu... 5M€ Cerrado

TIN2012-37546-C03-03 CORAZON HUMANO FISIOLOGICO VIRTUAL: DESARROLLO DE HERRAMIENT... 23K€ Cerrado

DPI2016-75458-R MULTI-SCALE PHYSIOLOGY-DRIVEN COMPUTATIONAL TOOLS TO ASSIST... 347K€ Cerrado

Líder del proyecto

UNIVERSITE DE BORDEAUX No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Cardiovascular disease is the first cause of mortality in the whole world (WHO 2008), responsible for 700000 deaths each year in Europe; a huge burden on healtcare. Half of this mortality is due to heart failure (HF), which can be caused or further aggravated by electrical dyssynchrony. The other half of cardiac mortality occurs suddenly, essentially due to ventricular tachyarrhythmias. The main objectives of SYMPHONY are (i) to advance our fundamental understanding in the mechanisms underlying SCD and electrical dyssynchrony in HF, with a strong focus on the specialized ventricular conduction network, and (ii) to improve current preventive, diagnostic and treatment methods for these life-threatening cardiac electrical disorders. SYMPHONY is a multidisciplinary project that will benefit from a wide array of state-of-the-art methodologies and expertise, both in fundamental and clinical sciences. A large mammalian species, the sheep, will be used for a detailed characterization of the properties of the conduction network in health and disease. Importantly, a limited number of explanted human hearts will be available on which all these techniques will equally be applicable. From our clinical work, SYMPHONY will benefit from cutting edge tools in epicardial and catheter mapping allowing simultaneous mapping of the Purkinje system and ventricular substrate. The gathered data will be fed into large-scale computer models that will allow personalized investigations into the mechanisms of SCD and electrical dyssynchrony. SYMPHONY has a significant potential for industrial valorisation and is likely to introduce new targets for interventions, and new methods for risk stratification and prevention. Therefore we can affirm that this unprecedented, comprehensive and translational project will lead to major advances in scientific knowledge, will have a significant impact on healthcare budgets and, most importantly, will dramatically improve quality of life and patient care.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores