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SE3DPASTE

Financiado

Structurally Engineered 3D Printed Architectures for Scalable Tissue Engineering

Engineering tissues with a hierarchical vascular network, which is the goal of our ERC project VascArbor, is challenging. Developments in the field of biofabrication, including 3D bioprinting, are promising to cope with this chall... ver más

28/02/2021

UNIVERSITEIT TWENT...

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

UNIVERSITEIT TWENTE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2021-02-28

ERC-2019-POC: ERC Proof of Concept Grant

I+D

Cerrada hace 5 años

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2 Participantes

UNIVERSITEIT TWENTE

150.00K€ | Lider

FAINSA - FABRICACION DE ASIE...

539.28K€ | Participante

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Duración del proyecto: 21 meses Fecha Inicio: 2019-05-16
Fecha Fin: 2021-02-28

Líder del proyecto

UNIVERSITEIT TWENTE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto Engineering tissues with a hierarchical vascular network, which is the goal of our ERC project VascArbor, is challenging. Developments in the field of biofabrication, including 3D bioprinting, are promising to cope with this challenge. However, current strategies lack the capacity to create hierarchical, high resolution, cost efficient, upscalable constructs in a standardized manner with a single approach. Embedded bioprinting, allowing the deposition of complex constructs without the need of a supporting substrate, provides a potential solution. However, embedding baths used so far consist of inert materials and therefore cannot become a functional component of the tissue. Also, the embedding bath should be patternable to allow for multistructural tissues, but printing of the bath itself is currently challenging due to clogging of the nozzle. SE3DPASTE will develop a dehydrated precursor of a free standing embedding bath that is storable for off-the-shelf use and tissue specific. Additionally, SE3DPASTE will develop a bespoke 3D printing nozzle that will allow for the creation of patterned embedding baths. SE3DPASTE will lead to storable, transportable, tissue specific embedding baths that act as a patterning template and can be used for embedded bioprinting of tissue. This combination of features, which does currently not exist in embedding baths for 3D printing, will be a key enabler for the generation of standardized 3D tissue environments that lead to predictable tissue development for research-, clinical-, or drug screening purposes. SE3DPASTE will not only develop the technology to make this possible, but will also take vital steps to bring this technology to the market. By securing the IP, and analyzing the market and the willingness of investors to support SE3DPASTE technology, a fruitful basis for translation will be formed. Finally, this will lead to a business plan providing a roadmap on the necessary future steps to create a market ready product.

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