Innovating Works

STEDGate

Financiado
STED-enabled super-resolution multimode-fibre based holographic endoscopy for de...
STED-enabled super-resolution multimode-fibre based holographic endoscopy for deep-tissue observations of neuronal connectivity Neurological disorders have emerged as a significant global societal burden, exemplified by afflictions like Alzheimer's and Parkinson's, impacting over one billion individuals globally and surpassing the combined economic burden... Neurological disorders have emerged as a significant global societal burden, exemplified by afflictions like Alzheimer's and Parkinson's, impacting over one billion individuals globally and surpassing the combined economic burden of cancer and diabetes. This has spurred a concerted global effort, with increased support for neuroscience research. These disorders often target deep brain regions and profoundly influence the structural connectivity of neuronal cells within functional circuits. Synapses, where neurons exchange information, exhibit plasticity, altering information transmission efficiency, shape, and position. Understanding the mechanisms underlying these structural changes, especially in neuronal circuits, remains limited in both healthy and affected individuals. The ERC PoC project STEDGate seeks to advance our understanding of neuronal connectivity and plasticity by developing STED-enabled holographic endo-nanoscopy for neuroscience. This ground-breaking technology promises atraumatic nanoscale in-vivo imaging of deep brain structures reaching depths up to 5 mm beneath the brain's surface. Collaborating with the start-up endeavour DeepEn, the team aims to facilitate the commercial transition of this technology. Making deep-tisue nanoscopy available globally will revolutionize our ability to monitor and understand neurological disorders and, ultimately, offer new avenues for intervention and treatment.. ver más
31/10/2025
150K€
Perfil tecnológico estimado
Duración del proyecto: 19 meses Fecha Inicio: 2024-03-25
Fecha Fin: 2025-10-31

Línea de financiación: concedida

El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-03-25
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
LEIBNIZINSTITUT FUER PHOTONISCHE TECHNOLOGIEN... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5