Spidersilk fibers as scaffold for tissue engineering skin regeneratin and wound...
Silk from silkworms has been used by man for thousands of years. Spiders, however, are territorial and not subject to domestication. Consequently, their silk, which is much stronger than that of silkworms, cannot be grown in comme...
Silk from silkworms has been used by man for thousands of years. Spiders, however, are territorial and not subject to domestication. Consequently, their silk, which is much stronger than that of silkworms, cannot be grown in commercial quantities. To overcome this problem, scientists have attempted to create synthetic spidersilk through genetic engineering of its proteins by means of bacteria, yeast, plants, mammalian cells in tissue culture, and even transgenic goats, but fibers resulting from these efforts have proven dissimilar or inferior to natural spidersilk. Seevix has overcome the technology barrier and produces fibers identical to the fibers in nature.
Seevix’s fibers can be used as scaffolds for tissue engineering and wound closure, and can support true 3D cell growth. Seevix spidersilk fibers improve the viability, function and overall health of cell culture at several levels. Our fibers conserve cell function over time, delay cell death and maintain spheroid integrity even during prolonged culturing. These effects were demonstrated in primary cell lines used in drug and toxicity screenings, as well as in proliferating cell lines. Seevix expects to introduce its first revenue generating 3D cell culture product into the market in 2018. The Phase-1 is an excellent instrument to accelerate the risk analysis and define a suitable strategy to boost the market introduction of Seevix fibers at international level, bringing key conclusions for the company about the target segments, market size and internal operational and financial needs to successfully deploy a strategic growth plan to take advantage of the huge market opportunity.ver más
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