Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

TEMPO

Financiado

Cerrado

Solving the 'time puzzle' of epigenetic effects on child mental health

TEMPO aims to solve the newly discovered epigenetic 'time puzzle' of child mental health. Recently it has been observed that common mental health problems in children (e.g. hyperactivity, poor impulse-control) are associated with... ver más

31/05/2027

ERASMUS MC

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-03-18

ERC-2021-STG: ERC STARTING GRANTS Scope:Objectives

I+D

Cerrada hace 3 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

ERASMUS MC

1.50M€ | Lider

Proyectos interesantes

Youth-GEMs

Medical Technol...

Data Science

8M€ Cerrado

CAPICE

Medical Technol...

Data Science

3M€ Cerrado

MHINT

Medical Technol...

Data Science

1M€ Cerrado

Youth-GEMs

Medical Technol...

Data Science

8M€ Cerrado

SEEM

Medical Technol...

Data Science

205K€ Cerrado

DIGIPARENT

Medical Technol...

Data Science

2M€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Duración del proyecto: 62 meses Fecha Inicio: 2022-03-18
Fecha Fin: 2027-05-31

Líder del proyecto

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto TEMPO aims to solve the newly discovered epigenetic 'time puzzle' of child mental health. Recently it has been observed that common mental health problems in children (e.g. hyperactivity, poor impulse-control) are associated with epigenetic patterns at birth - a mechanism that regulates gene activity in response to genetic and environmental influences. Curiously, however, this association is lost when measuring the same epigenetic patterns later in development. This discovery is highly unexpected and potentially ground-breaking: the existence of timing effects could lead to new insights into the origins of mental health and open much-needed opportunities for early risk detection. Yet, what factors drive epigenetic timing effects, how they manifest and why they occur is currently a puzzle. To solve it, TEMPO will combine innovative, multidisciplinary approaches and the generation of exceptional new data in a unique set of longitudinal European cohorts to address the what, where and why of epigenetic timing effects. Three work packages will be implemented to: (i) Systematically characterize unknown properties of epigenetic timing effects, including their genomic scale, specificity to mental health and persistence into adulthood, using advanced quantitative methods; (ii) Locate epigenetic timing effects with greater precision, by establishing whether effects are driven by epigenetic patterns in specific tissues and cell-types that are found at birth but not later in life; and (iii) Explain timing effects, by disentangling the genetic and environmental origins of epigenetic timing effects on mental health, drawing on the power of genetically sensitive, quasi-experimental designs. As well as leading a breakthrough in this emerging field and addressing a major knowledge gap at the intersection of biological and psychological sciences, TEMPO has the potential to set in motion a paradigm shift in the way that we conceptualize, understand and approach child mental health.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores