Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

BUCKLING BRIDGES

Financiado

Smart wavy patterned implants with instructive properties for tissue regeneratio...

Smart wavy patterned implants with instructive properties for tissue regeneration by controlling the degree of fibers buckling. In the pursuit for engineering CELL HYBRIDGE regenerative medicine implants able to regenerate skeletal tissues by controlling adult stem cell activity, we have developed an innovative method to successfully improve cell migration... ver más

31/12/2019

UNIVERSITEIT MAAST...

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

UNIVERSITEIT MAASTRICHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-12-31

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-2017-PoC: ERC-Proof of Concept

I+D

Cerrada hace 7 años

0% 100% 100%

2 Participantes

UNIVERSITEIT MAASTRICHT

150.00K€ | Lider

REMOSA

228.72K€ | Participante

Proyectos interesantes

SAF2014-52632-R ANDAMIAJES DINAMICOS MULTIFUNCIONALES PARA REGENERACION DE H... 169K€ Cerrado

HYDROCUP The hydrocup: a hollow electrospun scaffold for in vivo cell... 150K€ Cerrado

MAT2015-68906-R DESARROLLO DE PARTICULAS POLIMERICAS PARA GENERAR MATRICES E... 242K€ Cerrado

METABOLATE METABOLic immuno-engineered biomATErials 242K€ Cerrado

MAT2009-14195-C03-02 EVALUACION BIOLOGICA DE MATERIALS BIOACTIVOS, BIOMIMETICOS Y... 61K€ Cerrado

PersonalBone Multifunctional Personalized Self Assembled Biomaterials for... 1M€ Cerrado

Últimas noticias

30-11-2024: Cataluña Gestión For... Se ha cerrado la línea de ayuda pública: Gestión Forestal Sostenible para Inversiones Forestales Productivas para el organismo:

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

Duración del proyecto: 24 meses Fecha Inicio: 2017-12-08
Fecha Fin: 2019-12-31

Líder del proyecto

UNIVERSITEIT MAASTRICHT

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto In the pursuit for engineering CELL HYBRIDGE regenerative medicine implants able to regenerate skeletal tissues by controlling adult stem cell activity, we have developed an innovative method to successfully improve cell migration into electrospun scaffolds. Whereas this has a direct impact in CELL HYBRIDGE as part of the planned activities, we unexpectedly discovered that the same scaffolds display wavy patterns that have a direct influence on cell differentiation by enhancing their intrinsic capacity to produce growth factors. Driven by these observations, we have optimized the methodology and are able today to control the formation of such wavy patterns at a single fiber as well as multiple fiber scales by controlling the degree of buckling that the fibers are exposed to during processing. In doing so, we can reproduce the same waviness that is observed in several native tissues, among which tendons and ligaments. The aim of BUCKLING BRIDGES is to further investigate these instructive scaffolds as potentially smart implants for the regeneration of anterior cruciate ligaments. This will be done by further confirming our in vitro data and proof our concept by showing successful ligament regeneration in a preclinical animal model. While doing so, we will also explore the market potential of such products and develop a business plan for the creation of a spin-off company: TISSUE BRICKS.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores