SMART
Financiado
Smart Crystal Nucleation near Interface Dynamics in Active Pharmaceutical Ingred...
One of the most important challenges that drug development researchers face today is the low aqueous solubility of the active pharmaceutical ingredients (APIs). Most of the drug molecules under investigation exhibit poor water sol...
One of the most important challenges that drug development researchers face today is the low aqueous solubility of the active pharmaceutical ingredients (APIs). Most of the drug molecules under investigation exhibit poor water solubility and additional efforts are required to improve their solubility feature. Thus, the development of amorphous drugs is the most effective way how to improve the bioavailability of the APIs, and huge amount of effort is directed towards this smart approach. The aim of this project is to develop a reliable and universally applicable dynamic physio-chemical procedure for the description of the interconnection between the microscopic and macroscopic description of the triggered phase transformation – a task that would lay fundamental principles for the prediction of the macroscopic manifestation of the sub & near-Tg crystal growth in the class III amorphous drugs. This proposal is ‘SMART’ as this is first case of designing the unique green, dynamic and advanced molecular crystal nucleation near interface. In addition, the SMART project also aims to develop the combined experimental and mathematical procedural approach for fast, reliable, and accurate projections of the sub & near-Tg amorphous-to-crystalline dynamic transformation in amorphous APIs.
ver más
Duración del proyecto: 27 meses
Fecha Inicio: 2023-03-23
Fecha Fin: 2025-06-30
Fecha Fin: 2025-06-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-03-23
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2022-PF-01-01:
MSCA Postdoctoral Fellowships 2022
Cerrada
hace 2 años
Presupuesto
El presupuesto total del proyecto asciende a
207K€
Líder del proyecto
INSTITUTE OF ADVANCED MATERIALS IAAM AB
No se ha especificado una descripción o un objeto social para esta compañía.
