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SIMDEQ

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SIngle Molecule DEtection and Quantification SIMDEQ A new platform for geneti...

SIngle Molecule DEtection and Quantification SIMDEQ A new platform for genetic and epigenetic analysis The purpose of the proposed project is to investigate the commercialisation potential of an innovative technology that has been developed in my lab with ERC funding. For over 15 years, our laboratory at the Ecole Normale Supérieu... ver más

30/04/2016

CNRS

149K€

Presupuesto del proyecto: 149K€

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2016-04-30

ERC-PoC-2014: ERC Proof of Concept Grant Scope:Objectives

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

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4 Participantes

CNRS

148.50K€ | Lider

IMMODO SOLAR

523.71K€ | Participante

MONTAJES ELECTRICOS TUDELANO...

IMMODO RENTA SOL, S.L.

343.66K€ | Participante

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Duración del proyecto: 18 meses Fecha Inicio: 2014-10-23
Fecha Fin: 2016-04-30

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 149K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The purpose of the proposed project is to investigate the commercialisation potential of an innovative technology that has been developed in my lab with ERC funding. For over 15 years, our laboratory at the Ecole Normale Supérieure of the Centre Nationale de la Recherche Scientifique (CNRS) has been developing an instrument called a ‘magnetic trap’. Initially developed in order to study the mechanisms of DNA replication and repair, we have discovered in the past few years that this instrument can also be used to extract both genetic and epigenetic information from single molecules of DNA. The highly novel approach we have developed is called SIMDEQTM (short for ‘SIngle-molecule Magnetic DEtection and Quantification’). We have shown that it can be used to rapidly identify, map, quantify, and fully sequence DNA fragments present in a genetic sample. In addition, a unique feature of the technology is that it can detect and locate the naturally-occurring biochemical modifications to DNA’s four bases (e.g. methylation). There is substantial commercial interest in reading these ‘epigenetic’ modifications as they are important in areas such as developmental biology, cancer, and microbial virulence. The SIMDEQTM approach to genetic analysis is simple, elegant, and combines the DNA mapping and sequencing abilities of current instruments with the revolutionary ability to directly detect a wide range of DNA modifications at single base resolution. We believe SIMDEQTM could be a disruptive technology across a wide range of research and diagnostics sectors, but recognize that this is a dynamic field with many competitors and specialized niches. We therefore hope to investigate the market potential of this technology and identify the most promising applications through the work described in this proposal.

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