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LifeLongJoints

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Silicon Nitride Coatings for Improved Implant Function

Articulating joint replacements represent a medical market exceeding €14 billion p.a. that is expected to rise as demographics reflect an ageing population. However, faster growth has been seen in the revision market, where prosth... see more

31/03/2018

UNIVLEEDS

18M€

Project Budget: 18M€

Project leader

UNIVERSITY OF LEEDS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo FP7 notifico la concesión del proyecto The day 2018-03-31 We do not have the information of the call

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

12 Participantes

UNIVLEEDS

0.00€ | Leader

TUTECH INNOVATION GMBH

N.D. | participant

IMPERIAL COLLEGE OF SCIENCE...

N.D. | participant

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Project leader

UNIVERSITY OF LEEDS No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 18M€

participation deadline Sin fecha límite de participación.

Project description Articulating joint replacements represent a medical market exceeding €14 billion p.a. that is expected to rise as demographics reflect an ageing population. However, faster growth has been seen in the revision market, where prosthetic joints are replaced, than in primary interventions. The major cause of these revisions is that all joint replacements are prone to wear leading to loss of implant function. Further, it has been demonstrated that adverse or extreme loading has a detrimental effect on implant performance. Thus, device failure still occurs too frequently leading to the conclusion that their longevity and reliability must be improved. The premise of this proposal is to realise that wear and corrosion are an inevitable consequence of all implant interfaces within contemporary total joint replacements. To overcome this problem our novel approach is to use silicon nitride coatings in which the combined high wear resistance of this material and solubility of any silicon nitride wear particles released, reduce the overall potential for adverse tissue reactions. In this work a variety of silicon nitride based coatings will be applied to different tribological scenarios related to total hip arthroplasty. The coatings’ suitability in each scenario will be assessed against target profiles. In particular, it is important to consider coating performance within each of these applications under adverse conditions as well as those outlined in internationally utilised standards. To accomplish this, cutting-edge adverse simulation techniques, in vitro assays and animal models will be developed together with a suite of computational assessments to significantly enhance device testing in terms of predicting clinical performance. Data will inform new standards development and enhance current testing scenarios, and will provide 5 European enterprises with a significant market advantage, whilst providing data for a regulatory submission which is aligned with Dir 93/42/EEC.

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