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SEROTONIN and BEYOND

Financiado

Serotonin and BEYOND Brain development research Excelling Young Ones in Neurote...

Serotonin and BEYOND Brain development research Excelling Young Ones in Neurotechnologies and Discoveries Serotonin is a neurotransmitter playing a crucial in the onset and treatment of neuropsychiatric disorders. Most of the drugs currently used in psychiatry target serotonin (neuro)transmission. However, it is becoming increasingly... ver más

31/12/2024

RADBOUDUMC

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRU... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 13 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2020-08-28

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

MSCA-ITN-2020: Innovative Training Networks

I+D

Cerrada hace 4 años

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13 Participantes

RADBOUDUMC

265.62K€ | Lider

VCN BIOSCIENCES

1.08M€ | Participante

ERASMUS MC

265.62K€ | Participante

STICHTING RADBOUD UNIVERSITE...

531.24K€ | Participante

Últimas noticias

27-11-2024: Videojuegos y creaci... Se abre la línea de ayuda pública: Ayudas para la promoción del sector del videojuego, del pódcast y otras formas de creación digital

27-11-2024: DGIPYME En las últimas 48 horas el Organismo DGIPYME ha otorgado 1 concesiones

27-11-2024: FUNDACION-EOI En las últimas 48 horas el Organismo FUNDACION EOI ha otorgado 2 concesiones

Duración del proyecto: 52 meses Fecha Inicio: 2020-08-28
Fecha Fin: 2024-12-31

Presupuesto del proyecto 4M€

Descripción del proyecto Serotonin is a neurotransmitter playing a crucial in the onset and treatment of neuropsychiatric disorders. Most of the drugs currently used in psychiatry target serotonin (neuro)transmission. However, it is becoming increasingly clear that the efficacy of these drugs is suboptimal. As a result, the prevalence and burden of these disorders remain high. A new wave of research revealed that serotonin plays important role in neurodevelopment. Changes in serotonin levels lead to changes in developmental processes with consequences for the serotonin system and beyond. This makes it plausible that the origins of these disorders do not per se lie in disturbed serotonin neurotransmission, but rather in serotonin-mediated neurodevelopmental changes. This would require a radical different view on disease burden reduction. We hypothesize that it are the serotonin-mediated non-serotonergic downstream changes in neurodevelopment that are at the basis of serotonin-related neuropsychiatric disorders. SEROTONIN and BEYOND will establish an interdisciplinary, intersectoral and international scientific network to test this hypothesis. It will enable paradigm shifts in the understanding of vulnerability to neuropsychiatric disorders, and provide groundwork for critical windows in development for future interventions. To achieve these goals, top-class academic and industrial scientists will train Early Stage Researchers (ESRs) in the full spectrum of state-of-the-art neuroscientific technical approaches. We will also equip these ESRs with translational and entrepreneurial thinking by providing intersectoral and transferable skills training. In summary, we will train a new generation of ESRs in the integrated field of serotonin, neurodevelopment and psychiatry to deliver 15 excellent young researchers who are optimally prepared for their future academic and industrial careers.

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