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SEROTONIN and BEYOND

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Serotonin and BEYOND Brain development research Excelling Young Ones in Neurote...

Serotonin and BEYOND Brain development research Excelling Young Ones in Neurotechnologies and Discoveries Serotonin is a neurotransmitter playing a crucial in the onset and treatment of neuropsychiatric disorders. Most of the drugs currently used in psychiatry target serotonin (neuro)transmission. However, it is becoming increasingly... see more

31/12/2024

RADBOUDUMC

4M€

Project Budget: 4M€

Project leader

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRU... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 13 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2024-12-31

MSCA-ITN-2020: Innovative Training Networks Objective:The Innovative Training Networks (ITN) aim to train a new generation of creative, entrepre...

I+D

Cerrada does 5 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

13 Participantes

RADBOUDUMC

265.62K€ | Leader

VCN BIOSCIENCES

1.08M€ | participant

ERASMUS MC

265.62K€ | participant

STICHTING RADBOUD UNIVERSITE...

531.24K€ | participant

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Project duration: 52 months Date Start: 2020-08-28
End date: 2024-12-31

Project leader

STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRU... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 4M€

participation deadline Sin fecha límite de participación.

Project description Serotonin is a neurotransmitter playing a crucial in the onset and treatment of neuropsychiatric disorders. Most of the drugs currently used in psychiatry target serotonin (neuro)transmission. However, it is becoming increasingly clear that the efficacy of these drugs is suboptimal. As a result, the prevalence and burden of these disorders remain high. A new wave of research revealed that serotonin plays important role in neurodevelopment. Changes in serotonin levels lead to changes in developmental processes with consequences for the serotonin system and beyond. This makes it plausible that the origins of these disorders do not per se lie in disturbed serotonin neurotransmission, but rather in serotonin-mediated neurodevelopmental changes. This would require a radical different view on disease burden reduction. We hypothesize that it are the serotonin-mediated non-serotonergic downstream changes in neurodevelopment that are at the basis of serotonin-related neuropsychiatric disorders. SEROTONIN and BEYOND will establish an interdisciplinary, intersectoral and international scientific network to test this hypothesis. It will enable paradigm shifts in the understanding of vulnerability to neuropsychiatric disorders, and provide groundwork for critical windows in development for future interventions. To achieve these goals, top-class academic and industrial scientists will train Early Stage Researchers (ESRs) in the full spectrum of state-of-the-art neuroscientific technical approaches. We will also equip these ESRs with translational and entrepreneurial thinking by providing intersectoral and transferable skills training. In summary, we will train a new generation of ESRs in the integrated field of serotonin, neurodevelopment and psychiatry to deliver 15 excellent young researchers who are optimally prepared for their future academic and industrial careers.

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