Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

TNP-HGNS

Financiado

Cerrado

Self Assembled Thermo NanoProbes on Hollow Gold Nanoparticles For Theragnostic A...

Self Assembled Thermo NanoProbes on Hollow Gold Nanoparticles For Theragnostic Applications The functionally controllable molecules that are activated upon irradiation, have received a significant attention as nano-scale delivery tools in biomedical applications. Among these, photolabile caged therapeutic molecules are c... ver más

31/05/2013

75K€

Presupuesto del proyecto: 75K€

Líder del proyecto

GAZI UNIVERSITESI No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2013-05-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

0.00€ | Lider

Proyectos interesantes

MAT2008-01489

Nanotechnology

Medical Technol...

206K€ Cerrado

NORTH

Nanotechnology

Medical Technol...

1M€ Cerrado

CodeSphere

Nanotechnology

Medical Technol...

150K€ Cerrado

CTQ2017-83961-R

Nanotechnology

Medical Technol...

71K€ Cerrado

RADDEL

Nanotechnology

Medical Technol...

4M€ Cerrado

nano-PhotoMed

Nanotechnology

Medical Technol...

15K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

GAZI UNIVERSITESI No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 75K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The functionally controllable molecules that are activated upon irradiation, have received a significant attention as nano-scale delivery tools in biomedical applications. Among these, photolabile caged therapeutic molecules are chemically blocked species which can be liberated in their active form by exposure to ultraviolet (UV) radiation. By precise tuning of UV source, the use of these photosensitive probes becomes a unique tool to treat a selected biological target spatially and temporally. This technique has been successfully employed in a variety of biological studies; however, it is mostly limited to in vitro applications. The restriction is mainly due to the destructive effects of UV light which has shallow tissue penetration with strong absorption. Quite the contrary, near-infrared (NIR) radiation is known to have deep tissue penetration with minimum absorption. This outstanding property of NIR, with the aid of strong NIR absorbers, can be utilized to trigger a mechanism in cells for therapeutic and diagnostic (theragnostic) purposes. Among other metal nanoparticles that have been extensively studied for such purposes, gold nanoparticles, such as hollow gold nanostructures (HGNs), emerge as ideal tools for these applications since they possess optical tunability, easy functionalization, inertness, non-toxic behavior, accumulation in tissues, and intense absorption of NIR light. During the NIR absorption process, the absorbed energy by HGNs will be transferred into thermal energy that consequently heats the surroundings. This NIR mediated heating process can be employed for thermal cleavage of chemical bonds within the molecules, so called thermolabile caged compounds. This project proposes a novel design and synthesis of NIR driven thermolabile caged molecules as a nano-scale delivery tool, and their self-assembly on HGNs for targeted therapy and optical imaging applications.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores