Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SPRINTT

Financiado

Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strat...

Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from th... ver más

30/04/2020

SARD

56M€

Presupuesto del proyecto: 56M€

Líder del proyecto

SANOFIAVENTIS RECHERCHE DEVELOPPEMENT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 25 Participantes

Financiación concedida El organismo FP6 notifico la concesión del proyecto el día 2020-04-30 No tenemos la información de la convocatoria

0% 100%

25 Participantes

SARD

Lider

SERMAS

N.D. | Participante

FAU

N.D. | Participante

UNIVERSITA DEGLI STUDI DI PA...

N.D. | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

PID2019-108408RB-C22 ACTIVEUP: DIMENSION CIENTIFICA Y CLINICA 49K€ Cerrado

PID2020-117579RA-I00 VISITAS DE ESTUDIANTES DE ENFERMERIA A ADULTOS MAYORES CON M... 34K€ Cerrado

DEP2013-47786-R VALORACION OBJETIVA DE LA ACTIVIDAD FISICA Y SU IMPACTO EN E... 97K€ Cerrado

EQC2019-006406-P Unidad de valoración y Ejercicio físico de precisión para la... 57K€ Cerrado

PID2019-110747RB-C21 VALORACION DE LA MOVILIDAD DE PACIENTES CRONICOS COMPLEJOS Y... 65K€ Cerrado

PID2020-113788RB-I00 IDENTIFICACION DE FACTORES DE RIESGO Y BIOMARCADORES DE VULN... 86K€ Cerrado

Duración del proyecto: 69 meses Fecha Inicio: 2014-07-01
Fecha Fin: 2020-04-30

Líder del proyecto

SANOFIAVENTIS RECHERCHE DEVELOPPEMENT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 56M€

Descripción del proyecto The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from the expansion of an older population with specific medical needs related to multiple chronic disorders. As a consequence, the medical conditions of a large and growing segment of the older European population are not efficiently managed by the available healthcare services. Among these conditions, the geriatric syndrome of frailty has emerged as a significant public health priority. It is defined as a multidimensional condition characterised by decreased reserve and diminished resistance to stressors. Such extreme vulnerability exposes the older individual to an increased risk of morbidity, disability, inappropriate healthcare use, institutionalization, poor quality of life, and death. Early detection and prevention of frailty are thus crucial to impede its progression and the development of its detrimental clinical consequences, while ensuring sustainability of healthcare systems of the Member States. Unfortunately, to date, no healthcare programs or pharmacological treatments are available for frail older people. This is largely due to the lack of a precise, universal definition of frailty, linked in turn to the multidimensional nature of the condition. Eventually, the existing gaps in knowledge are reflected by the absence of effective interventions. Such a barrier may be overcome by developing and validating a robust conceptual framework to achieve a practical operationalisation of frailty. This should precisely define its pathophysiological and clinical foundations, to assist in the design and implementation of specific interventions aimed at restoring robustness and delaying the onset of adverse outcomes. The present Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) project is specifically designed to overcome the existing barriers for an efficient public health intervention against frailty, and promote the implementation of successful aging strategies across Europe. To reach such an ambitious goal, the actions of the SPRINTT Consortium are directed towards the achievement of a consensus among academia, regulators, industry (pharmaceutical and medical devices), and patients’ representatives over (1) clear operationalisation of the presently vague concept of frailty; (2) identification of a target population with unmet medical needs; (3) evaluation and validation of methodologies for implementing preventive and therapeutic strategies among frail elders at risk of disability in the European Union; (4) definition of an experimental setting as a template for regulatory purposes and pharmaceutical investigations; (5) identification of biomarkers and health technology solutions to be implemented into clinical practice. Thus, the project is expected to pursue all the research deliverables described in nine work-packages.The SPRINTT project proposes a novel operationalisation of physical frailty recognising sarcopenia as its central biological substrate. This approach is based on the fact that the physical frailty phenotype overlaps substantially with sarcopenia. Indeed, many of the adverse outcomes of frailty are probably mediated by sarcopenia, which may therefore represent both the biological substrate for the development of physical frailty and the pathway through which the negative health outcomes of frailty ensue. Although physical frailty encompasses only a part of the frailty spectrum, the identification of a definite biological basis (i.e., skeletal muscle decline and loss of mobility function) opens new venues for the development of interventions to slow or reverse the progression of this condition. It is noteworthy that all of the components characterising the Physical Frailty and Sarcopenia (PF&S) model are measurable and qua

Conecta tu I+D

Entra hoy

¿Olvide mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores