Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SC-Foxy

Financiado

Resolving temporal immune responses of Arabidopsis roots to infection by Fusariu...

Resolving temporal immune responses of Arabidopsis roots to infection by Fusarium oxysporum at the single-cell level Pathogen-caused diseases represent one of the biggest problems in agriculture. A detailed mechanistic understanding of plant defenses against pathogenic invasion and disease progression is therefore a vital research topic, forming... ver más

09/03/2025

MPG

190K€

Presupuesto del proyecto: 190K€

Líder del proyecto

MAXPLANCKGESELLSCHAFT ZUR FORDERUNG DER WISSE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-02-28

HORIZON-MSCA-2022-PF-01-01: MSCA Postdoctoral Fellowships 2022 ExpectedOutcome:

I+D

Cerrada hace 2 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

MPG

189.69K€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

BFU2015-68199-R SOBRE LOS MECANISMOS DE SUSCEPTIBILIDAD A PATOGENOS EN ARABI... 290K€ Cerrado

PID2021-127450NB-I00 ANALISIS FUNCIONAL DE LA S-CIANILACION DE PROTEINAS MEDIADA... 133K€ Cerrado

PID2021-127982NB-I00 NUEVAS VIAS DE SEÑALIZACION DE DEFENSA EN PLANTAS DEPENDIENT... 157K€ Cerrado

BFU2012-32220 SOBRE LOS MECANISMOS DE CONTROL DE LA RESISTENCIA/SUSCEPTIBI... 433K€ Cerrado

IMMUNE-EXPRESS Proteasome Mediated Gene Expression in Plant Immunity 1M€ Cerrado

BES-2013-065010 RESISTENCIA DE ARABIDOPSIS THALIANA A PATOGENOS REGULADA POR... 84K€ Cerrado

Duración del proyecto: 24 meses Fecha Inicio: 2023-02-28
Fecha Fin: 2025-03-09

Líder del proyecto

MAXPLANCKGESELLSCHAFT ZUR FORDERUNG DER WISSE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 190K€

Descripción del proyecto Pathogen-caused diseases represent one of the biggest problems in agriculture. A detailed mechanistic understanding of plant defenses against pathogenic invasion and disease progression is therefore a vital research topic, forming the foundation for the creation of more resistant crop varieties. However, at present, most studies aimed at this utilize ‘omics’ approaches or mutant analyses, which lack resolution and only allow limited understanding of plant-pathogen interactions at the single-cell level. Thus, our current models of plant-pathogen interaction do not include strictly local or temporal responses. The aim of this proposal is to address this with a pathosystem consisting of the model plant Arabidopsis thaliana and strains of Fusarium oxysporum, a destructive fungal pathogen of several food crops. A unique near-native imaging setup, enabling the simultaneous study of growth and infection of plant and fungus with single-cell resolution, will be used. The work in this proposal will probe the responses of individual plant cells to both pathogenic and beneficial F. oxysporum strains, in a native tissue context from the onset of invasion to full disease development. This will generate novel insights into cellular mechanisms employed by plants to fight off pathogenic invaders, while accommodating beneficial endophytes. By using a novel in vivo cell-labeling technique, exploiting the fungal avirulence effector secretion system, a single-cell transcriptome atlas exclusively of cells undergoing acute colonization will be generated. Moreover, as root barriers represent a physical hindrance for pathogen invasion, mutants affected in physical defenses will be tested. Combined, this proposal will expand our current models of immune responses to include specific cells, regions or tissues, and temporal aspects with high resolution. Such knowledge is important to develop next-generation agricultural tools and will be applicable to combat current and arising diseases.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores