Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

REGENERBONE

Financiado

Cerrado

REGENERATING LARGE BONE DEFECTS

In the field of orthopedics and maxillo-facial surgeries, there is still no satisfying solution to repair critical size bone defects. Autograft, which is the current gold standard, presents several drawbacks, including prolonged p... ver más

30/09/2019

INP GRENOBLE

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

INSTITUT POLYTECHNIQUE DE GRENOBLE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 3 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-09-30

ERC-2017-PoC: ERC-Proof of Concept

I+D

Cerrada hace 8 años

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

3 Participantes

INP GRENOBLE

150.00K€ | Lider

QUALITEASY INTERNET SOLUTION...

CNRS

11.50K€ | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

REBORNE Regenerating Bone defects using New biomedical Engineering a... 15M€ Cerrado

BIO-INSPIRE BIO INSPIRED BONE REGENERATION 4M€ Cerrado

CHARME Growing bone fast and cost effective 3M€ Cerrado

DPI2017-82501-P REPARACION DE GRANDES DEFECTOS OSEOS: TRANSPORTE OSEO VERSUS... 123K€ Cerrado

MAGISTER Magnetic Scaffolds for in vivo Tissue Engineering 11M€ Cerrado

ADAPTOS ADAPTOS Changing the way bone voids are treated 3M€ Cerrado

Duración del proyecto: 18 meses Fecha Inicio: 2018-03-22
Fecha Fin: 2019-09-30

Líder del proyecto

INSTITUT POLYTECHNIQUE DE GRENOBLE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 150K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto In the field of orthopedics and maxillo-facial surgeries, there is still no satisfying solution to repair critical size bone defects. Autograft, which is the current gold standard, presents several drawbacks, including prolonged pain on donor site and higher infection risks. It needs to be replaced by efficient, safe and easy-to-use strategies. Some synthetic bone grafts are providing mechanical and osteoconductive properties, but there is a need to introduce a bioactive molecules, such as a growth factor or a peptide, to trigger actively bone repair. These orthobiologics products are appealing since they trigger stem cell activation in situ. There are several approved products containing orthobiologics on the market for bone regeneration, but the physiological delivery of orthobiologics remains a challenge: severe adverse effect have been reported due to the supra-physiological dose of biologics used. In addition these product do not provide structural properties which is necessary for critical size defect reconstruction. Ideally the carrier for the bioactive molecules should be appropriate and enable a spatially/temporally-controlled molecules delivery with physiological dose. Our nanomedicine technology consists of an osteoinductive biomimetic films that can be deposited on architectured implant of any shape and material (ceramics, polymers, metals). The aim of REGENERBONE is to advance our technology toward a clinical application in maxilla-facial surgery and orthopedics. This will be done by conducting pre-clinical trials in large animals, doing a market search, securing the sourcing of the film components and building a business model. The successful results we obtained recently in the frame of the ERC BIOMIM and Proof-of-Concept OSCODI are the basis for REGENERBONE, which goes a step beyond in the long process of introducing an innovative medical device to the market in an era of personalized medicine.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores