Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

DESIGN2HEAL

Financiado

Cerrado

Rational design of scaffold architecture and functionalization to induce healing...

Rational design of scaffold architecture and functionalization to induce healing and tissue regeneration When materials are implanted into the body they initiate an inflammatory response that is difficult to control. Consequently medical implants are tolerated by the body rather than fully integrated; the material is often sealed off... ver más

28/02/2019

KLINIKUM DER BAYER...

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

UNIVERSITAETSKLINIKUM WUERZBURG KLINIKUM DER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2019-02-28 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

KLINIKUM DER BAYERISCHEN JUL...

0.00€ | Lider

Proyectos interesantes

SAF2017-83118-R

Medical Technol...

Materials Scien...

127K€ Cerrado

DPI2017-88465-R

Medical Technol...

Materials Scien...

218K€ Cerrado

SAF2014-52632-R

Medical Technol...

Materials Scien...

169K€ Cerrado

DPI2010-20399-C04-03

Medical Technol...

Materials Scien...

208K€ Cerrado

BES-2011-046144

Medical Technol...

Materials Scien...

43K€ Cerrado

DPI2011-29216-C02-01

Medical Technol...

Materials Scien...

12K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

UNIVERSITAETSKLINIKUM WUERZBURG KLINIKUM DER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto When materials are implanted into the body they initiate an inflammatory response that is difficult to control. Consequently medical implants are tolerated by the body rather than fully integrated; the material is often sealed off from the body in a fibrotic capsule. Most recent research suggests that morphology is a decisive immunomodulatory trigger and may favor a healing-like reaction of the innate immune system, especially of macrophages. I have pioneered a single-step method to generate non-woven fibrous scaffolds with surface chemistry control that allows specific cell adhesion. Additionally, my laboratory recently established melt electrospinning writing (MEW) that allows automated scaffold production by solvent-free electrostatic drawing with precise morphology control through rational deposition of polymer filaments in micrometer resolution. Design2Heal is based on this world-wide unique combination of technologies and proposes to combine form (scaffold morphology) with function (surface chemistry) to generate biomaterials that are designed to heal and improve implant integration. Pioneering and ground breaking research within Design2Heal includes: • A single-step procedure to fabricate MEW scaffolds with controlled surface functionalities for specific bioactivation. • Unraveling the immunomodulatory potential of generic scaffold parameters (diameter, morphology) and surface functionalization (peptides, sugars, glycosaminoglycans) for rationally designed scaffolds in vitro with primary human innate immune cells. • Resolve the immunomodulatory effects of cellular cross-talk and interaction between human immune cells, mesenchymal stem cells and endothelial progenitor cells in defined geometric confinements. • In vivo proof-of-principle in the murine model In case of success, Design2Heal will be a ground breaking first step towards actively healing implants independently of the affected tissue, with tremendous impact on healthcare worldwide.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores