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RID-RTI

Financiado

Cerrado

Rapid Identification of Respiratory Tract Infections

Respiratory Tract Infections (RTIs) are caused by a variety of bacterial, viral, fungal and other pathogens. RTIs are major causes of morbidity and mortality in adults and children worldwide causing millions of deaths each year. R... ver más

31/12/2015

UNIVERSITY COLLEGE...

8M€

Presupuesto del proyecto: 8M€

Líder del proyecto

UNIVERSITY COLLEGE LONDON No se ha especificado una descripción o un objeto social para esta compañía.

Fecha límite participación Sin fecha límite de participación.

Ver 6 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2015-12-31 No tenemos la información de la convocatoria

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

6 Participantes

UNIVERSITY COLLEGE LONDON

1.58M€ | Lider

OLLSCOIL NA GAILLIMHE

N.D. | Participante

ASSISTANCE PUBLIQUE HOPITAUX...

N.D. | Participante

UCLH

N.D. | Participante

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Líder del proyecto

UNIVERSITY COLLEGE LONDON No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 8M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Respiratory Tract Infections (RTIs) are caused by a variety of bacterial, viral, fungal and other pathogens. RTIs are major causes of morbidity and mortality in adults and children worldwide causing millions of deaths each year. RTIs affecting the lung parenchyma (pneumonia) can be classified into three main categories: Community Acquired Pneumonia (CAP); Hospital Acquired Pneumonia (HAP) which includes Ventilator Associated Pneumonia (VAP); and opportunistic pathogens causing pneumonia in immunosuppressed patients (Opportunistic RTIs or ORTIs). RTIs are difficult to diagnose accurately and current standard microbiological culture based tests are laborious and time consuming with a turnaround time to results > 30 hours. Thus, all ill patients presenting with CAP, HAP, VAP or ORTIs are initially treated empirically with antibiotics, without an accurate identification of the causative microorganism and associated antibiotic susceptibility profile. This leads to inappropriate use of antibiotics, which can increase patient morbidity and mortality. Therefore, there is a great need for rapid molecular diagnostics tests capable of identifying a large range of microorganisms and antibiotic resistances rapidly and accurately so that appropriate therapy can be instituted on first consultation. Accurate pathogen identification and resistance profiling is also important for the epidemiological surveillance of pneumonia. The aims of the RiD-RTI project are (through a unique partnership of SMEs, universities and hospitals from 4 countries) to develop and evaluate three diagnostics products for the rapid diagnosis of CAP, HAP/VAP and ORTIs, based on a novel sample-in, answer-out diagnostic platform. The diagnostics products will be designed to be ‘near patient’, reliable, cost-effective and user friendly allowing for the rapid (< 2 hrs) and accurate detection, identification, quantification (for selected targets) and molecular drug susceptibility testing of RTIs.

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