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PROPATHIN

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PROtist PATHobiome INvertebrate interactions a multi approach to understand mar...

PROtist PATHobiome INvertebrate interactions a multi approach to understand marine diseases of commercial bivalves Marine disease outbreaks can devastate populations, alter community structure and affect ecosystem health, which results in biodiversity loses and economic impacts on ecosystem services. Bivalves, which mediate ecosystem processes... see more

31/08/2026

CSIC

165K€

Project Budget: 165K€

Project leader

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 552M€

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo HORIZON EUROPE notifico la concesión del proyecto The day 2023-04-24

HORIZON-MSCA-2022-PF-01-01: MSCA Postdoctoral Fellowships 2022 Expected Outcome:

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

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2 Participantes

CSIC

165.31K€ | Leader

INSTITUT DE RECERCA I TECNOL...

N.D. | participant

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Project duration: 40 months Date Start: 2023-04-24
End date: 2026-08-31

Project leader

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 2-3 | 552M€

Project Budget 165K€

participation deadline Sin fecha límite de participación.

Project description Marine disease outbreaks can devastate populations, alter community structure and affect ecosystem health, which results in biodiversity loses and economic impacts on ecosystem services. Bivalves, which mediate ecosystem processes and functions and provide ecosystem services (e.g. food), harbour a wide variety of protists in their microbiome, including parasites and pathogens. Protist species produce important economic losses on the world’s leading shellfish industries due to parasitic disease outbreaks in bivalve hosts and the transmission of pathogens affecting human health. Although the economic implications of these outbreaks in shellfish aquaculture are significant, very little is known regarding their biology and ecology. In this context, PROPATHIN project is designed to advance our knowledge on marine and food-borne diseases caused by microbial eukaryotes (protists) associated to commercial bivalves, through the multidisciplinary study of protist-bivalve interactions at molecular, cellular and community level. I will employ recently developed molecular (metabarcoding) and ‘omic techniques (single-cell genomics and transcriptomics) coupled with traditional cell biology methods for diagnose of infectious organisms in multicellular hosts. I will assess the diversity, composition and dynamics of oysters and mussels pathobiome in the Ebro Delta aquaculture setting during a year cycle. Environmental parameters will be used to assess the dynamics of such hazardous protists related to seasonal changes. Further, we will sequence the genome and transcriptome of a protist parasite (including different life-cycle stages), from which very little information exists, revealing the genes involved in the infection of bivalve hosts. Overall, PROPATHIN will help us disentangle the nature and dynamics of such host-parasite relationships, crucial to prevent and mitigate their negative economic and societal impacts.

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