Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

SynCellCluster

Financiado

Cerrado

Programmable synthetic cell communication via coacervate-mediated dynamic cluste...

Programmable synthetic cell communication via coacervate-mediated dynamic clustering The current global human crisis in climate, health and energy calls for the development of new biotechnological innovations. The engineering of living cells has demonstrated its efficiency to produce drugs or degrade pollutants, b... ver más

31/12/2026

CNRS

212K€

Presupuesto del proyecto: 212K€

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 2 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-04

HORIZON-MSCA-2023-PF-01-01: MSCA Postdoctoral Fellowships 2023 ExpectedOutcome:Project results are expected to contribute to the following outcomes:

I+D

Cerrada hace 1 año

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

CNRS

211.75K€ | Lider

IMPERIAL COLLEGE OF SCIENCE...

N.D. | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

IVMMHBCSS In Vivo Metabolite Modification in Hybrid Biological and Che... 282K€ Cerrado

BES-2016-078815 BIOELECTROCATALISIS CON HIDROGENASAS: PRODUCCION FOTOBIOELEC... 93K€ Cerrado

ARC-for-CORE Artificial Compartment for Coenzyme Regeneration 171K€ Cerrado

MicroLightProtoCell Microfluidics assisted design and construction of light resp... 173K€ Cerrado

BIOENERGY Biofuel Cells From fundamentals to applications of bioelec... 4M€ Cerrado

CTQ2017-89539-P LIBRERIAS CONSTITUCIONALES DINAMICAS CON PROPIEDADES "CELULA... 62K€ Cerrado

Duración del proyecto: 32 meses Fecha Inicio: 2024-04-04
Fecha Fin: 2026-12-31

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 212K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The current global human crisis in climate, health and energy calls for the development of new biotechnological innovations. The engineering of living cells has demonstrated its efficiency to produce drugs or degrade pollutants, but living cells also come with major limitations. Synthetic cells are human-made robust micro-compartments that reproduce key features of living cells from non-living matter, and are now being engineered to tackle key societal challenges of the European Union, including environmental clean-up, energy production or drug delivery. The integration of multiple functional modules in a single synthetic cell, required to perform complex tasks, remains yet a grand challenge. A promising alternative to increase the functionality of synthetic cells is to distribute multiple functions into specialized compartments able to communicate with each other through chemical signaling to perform tasks collectively. However, chemical communication between synthetic cells remains poorly controllable and programmable. The aim of this proposal is to develop a new platform to quantitatively study chemical signalling between synthetic cells based on their dynamic clustering. For this purpose, we will engineer switchable sticky coacervate droplets to selective interact with enzymatically active vesicles and promote their reversible clustering in response to light or pH. The bottom-up assembly of vesicles will be achieved by microfluidics due to modularity and reliability to produce structurally well-defined architectures. Optical tweezers will be used to study the coacervate-mediated interactions between vesicles and quantify their chemical signalling via confocal fluorescence microscopy and spectroscopy. The skills and experience of the candidate in stimuli-responsive biomaterials, polymer coatings and adhesion will be applied to the interdisciplinary and cutting-edge fields of synthetic cells in which the hosting groups have made progress in the recent past.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores