Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

ProBIOnCell

Financiado

Probing the cell ion channels with functionalized Atomic Force Microscopy tips a...

Probing the cell ion channels with functionalized Atomic Force Microscopy tips and electrodes tested on biomimetic membranes embedding ionophores The main goal of ProBIOnCell is to broaden my expertise by performing state-of-the-art scientific research in the fields of applied physics and cell biology by implementing functionalized AFM tips with natural and/or synthetic ion... ver más

01/09/2026

INCDFM

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

INSTITUTUL NATIONAL DE CERCETARE DEZVOLTARE P... No se ha especificado una descripción o un objeto social para esta compañía.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-25

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

HORIZON-WIDERA-2023-TALENTS-02-01: ERA Fellowships

I+D

Cerrada hace 1 año

0% 100%

1 Participantes

INCDFM

149.58K€ | Lider

Proyectos interesantes

PRE2020-092150 ESTUDIO BIOFISICO DE LOS MECANISMOS DE PERMEABILIZACION DE M... 99K€ Cerrado

PRE2020-094017 ESTUDIO BIOFISICO DE LOS MECANISMOS DE PERMEABILIZACION DE M... 99K€ Cerrado

FIS2010-19810 BIOFISICA MOLECULAR DE CANALES IONICOS CON INTERFASES CARGAD... 61K€ Cerrado

CNS2023-143803 Física aplicada y Biofísica 199K€ Cerrado

CNS2023-145460 Física aplicada y Biofísica 166K€ Cerrado

MechMCA Mechanics of the Membrane-Cortex Attachment 196K€ Cerrado

Últimas noticias

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

29-11-2024: CMVAMADRID En las últimas 48 horas el Organismo CMVAMADRID ha otorgado 37 concesiones

Duración del proyecto: 28 meses Fecha Inicio: 2024-04-25
Fecha Fin: 2026-09-01

Presupuesto del proyecto 150K€

Descripción del proyecto The main goal of ProBIOnCell is to broaden my expertise by performing state-of-the-art scientific research in the fields of applied physics and cell biology by implementing functionalized AFM tips with natural and/or synthetic ionophores incorporated into biomimetic membranes, for electrochemically testing their ability to detect target ions in cellular cultures, so that to probe and localize cell membrane ion channels, gap-junction and focal adhesion on mouse primary cardiac fibroblast cells. Advancing the characterization of biological cells allows for a deeper understanding and modeling the physiological behavior of biological tissues, with huge potentials in biomedicine for improving the management of cardiovascular diseases and their treatment. From a personal perspective, this project contributes to my first international mobility, which is fundamental for unlocking new career perspectives towards a permanent research position and will be implemented at the National Institute of Materials Physics (NIMP) of Bucharest. In order to achieve the main goal of ProBIOnCell some specific objectives are foreseen: O1. Membrane synthesis and ionophores incorporation. Bilipid membranes, hydrogels and liposomes will be synthesized and the incorporation of ionophores investigated. O2. Functionalization of electrodes and AFM tips. This objective involves the deposition or bottom-up construction of the membrane with embedded ionophores at the surface of electrodes and AFM tips. O3. Development of suitable control healthy and pathological fibroblast cell cultures, test the membrane capacity for the detection of target ions by electrochemical methods in the absence and in the presence of inhibitory compounds, and localize ion channels, gap junctions, and focal adhesions by AFM.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores