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PolarNet

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Principles of Polarity Integrating genetic biophysical and computational appr...

Principles of Polarity Integrating genetic biophysical and computational approaches to understand cell and tissue polarity The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of... ver más

30/09/2019

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

UNIVERSITEIT UTRECHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 13 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-09-30

MSCA-ITN-2015-ETN: Marie Skłodowska-Curie Innovative T... Scope:European Training Networks (ETN)

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

13 Participantes

1.28M€ | Lider

INSTITUT CURIE FONDATION

262.88K€ | Participante

525.75K€ | Participante

The Francis Crick Institute

273.29K€ | Participante

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Duración del proyecto: 49 meses Fecha Inicio: 2015-08-12
Fecha Fin: 2019-09-30

Líder del proyecto

UNIVERSITEIT UTRECHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The ability of cells to polarize underlies the most basic biological functions such as motility and response to external challenges, but also the formation and maintenance of tissues in a multicellular organism. The importance of cell polarity is underscored by the fact that cell polarity is essential for animal development and is perturbed in disease states such as cancer. Understanding cell polarity requires knowledge of the molecular players involved and a quantitative description of their biochemical interactions, as well as the mechanical processes underlying polarity establishment. PolarNet brings together academic and private partners from 7 European countries to establish a multidisciplinary, intersectoral training and research programme that will study the basic principles of cell polarity. The research will combine complementary model systems ranging from fungi and cultured mammalian cells to whole organisms, and employ a broad set of approaches such as advanced genetics, protein biochemistry, high-resolution live imaging and image analysis, biophysics and theoretical modelling. This setting provides an opportunity to train early stage researchers in a unique combination of experimental and theoretical approaches. This will provide an excellent starting point for a successful career in the rapidly expanding field of multidisciplinary or ‘integrative’ biology. Training Europe’s next generation of scientists at the forefront of cell and organismal polarity research is crucial for progress in several medically important fields, including cancer research and stem cell biology. The tight collaboration with non-academic partners will strengthen the technological base of different projects and provide early stage researchers with insights into the translation potential of the performed studies and the career development opportunities in biomedical industry.

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