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POLYBOOST

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POLYBOOST Renovating the Polyclonal Immunotherapy

Immunotherapy is an essential field of medicine that allows clinicians to stimulate or to suppress the response of our immune system against specific stimuli. The progressive ageing of the population and the rising incidence of ch... see more

31/03/2017

Xenothera

71K€

Project Budget: 71K€

Project leader

XENOTHERA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2017-03-31

SMEInst-05-2016-2017: Supporting innovative SMEs in the h...

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2 Participantes

Xenothera

50.00K€ | Leader

AVANTEA

N.D. | participant

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Project duration: 2 months Date Start: 2017-01-31
End date: 2017-03-31

Project leader

XENOTHERA No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 71K€

participation deadline Sin fecha límite de participación.

Project description Immunotherapy is an essential field of medicine that allows clinicians to stimulate or to suppress the response of our immune system against specific stimuli. The progressive ageing of the population and the rising incidence of chronic diseases is driving the demand for immunotherapy, as it can be used to fight cancer or autoimmune diseases. One of its major applications today is to prevent the rejection of transplanted organs. Since organs are scarce (+40,000 Europeans on waiting list), patients are administered high doses of polyclonal immunosuppressants for several days around the time of surgery to prevent rejection. However, current polyclonals are not safe or reliable. Patients respond to these products by developing severe side effects that increase the risk for death & the medical costs. Thus, current polyclonals are only open for one time use. Also, the transplanted organ is severely damaged in the process, reducing its life-survival. In response, the consortium XENOTHERA & AVANTEA has created this project with the main objective of bringing to market a unique platform for the production of safer polyclonals (POLYBOOST). Our innovative method will revolutionize the field of immunotherapy, since it enables production of customized polyclonal products of low antigenicity, which retain a full immunological effect but do not induce side effects. We have proven the efficiency of POLYBOOST by customizing a polyclonal for transplantation medicine. In views of this successful achievement, we now aim to move forward towards the market. Thus, in Phase 1 we plan to assess all the aspects influencing the project from the technical, commercial and financial perspectives. We believe POLYBOOST will bring huge benefits for society and medicine, entering the market with a so long waited for product that will disrupt transplantation medicine. In turn, we expect the project to impact our growth significantly, registering €352 M in revenues and hiring 41 new people in 5 years.

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