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POTENTIAL

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Platform Optimisation To Enable NanomaTerIAL safety assessment for rapid commerc...

Platform Optimisation To Enable NanomaTerIAL safety assessment for rapid commercialisation Advanced Nanomaterials (Ad-NMs) will lead a new industrial revolution and accelerate the transition to greener technologies and better health care. However, lack of practical and reliable protocols to evaluate Ad-NMs' potential ha... ver más

31/12/2026

IRFMN

3M€

Presupuesto del proyecto: 3M€

Líder del proyecto

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEG... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-11-24

HORIZON-CL4-2022-DIGITAL-EMERGING-01-35: Advanced characterisation methodolo... ExpectedOutcome:The development of reliable and practical tools to ensure the safe and sustainable u...

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13 Participantes

IRFMN

677.38K€ | Lider

ASOC CENTRO DE INVESTIGACION...

338.69K€ | Participante

MyB

193.55K€ | Participante

USPN

145.15K€ | Participante

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Duración del proyecto: 49 meses Fecha Inicio: 2022-11-24
Fecha Fin: 2026-12-31

Líder del proyecto

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEG... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 3M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Advanced Nanomaterials (Ad-NMs) will lead a new industrial revolution and accelerate the transition to greener technologies and better health care. However, lack of practical and reliable protocols to evaluate Ad-NMs' potential hazards and risks has hindered innovation so far. POTENTIAL will generate a methodological framework comprising a set of harmonised protocols for characterisation, testing, grouping and read-across of Ad-NMs, that meet regulatory requirements for risk assessment, by improving: a) Advanced imaging protocols to quantify and characterize the intrinsic and extrinsic properties of Ad-NMs in complex matrices, using conventional analytical methods. b) Protocols to trace the evolution of Ad-NMs properties throughout their lifecycle, and methodologies for accelerated testing. c) in vitro multi-cellular models, in vivo (invertebrate) models, and ecotoxicological models for assessing the environmental and health hazard of Ad-NMs. Grouping and read-across approaches will build up on results from existing Horizon initiatives (GRACIOUS, SUNSHINE and HARMLESS), and will generate novel algorithms for similarity assessment, grouping hypotheses and Integrated Approaches to Testing and Assessments (IATAs). The protocols generated in the project will be validated through peer-reviewed publications and disseminated in Open Access. Furthermore, we will engage with the relevant standardisation bodies and organisations (OECD, ISO, CEN) to ensure that our approach can be translated into industry standards. The consortium comprises 11 European partners and 1 international partner (China), among which 4 high-tech SMEs specialised in Ad-NMs, and a high-tech incubator / accelerator. POTENTIAL contributes to the Horizon Europe workprogram by helping establish appropriate methods for cost-efficient assessment and prediction of the health and environmental effects of Ad-NMs, as well as supporting the inclusion of new methods to support safe-and-sustainable-by-design.

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