Innovating Works

POTENTIAL

Financiado
Platform Optimisation To Enable NanomaTerIAL safety assessment for rapid commerc...
Advanced Nanomaterials (Ad-NMs) will lead a new industrial revolution and accelerate the transition to greener technologies and better health care. However, lack of practical and reliable protocols to evaluate Ad-NMs' potential ha... Advanced Nanomaterials (Ad-NMs) will lead a new industrial revolution and accelerate the transition to greener technologies and better health care. However, lack of practical and reliable protocols to evaluate Ad-NMs' potential hazards and risks has hindered innovation so far. POTENTIAL will generate a methodological framework comprising a set of harmonised protocols for characterisation, testing, grouping and read-across of Ad-NMs, that meet regulatory requirements for risk assessment, by improving: a) Advanced imaging protocols to quantify and characterize the intrinsic and extrinsic properties of Ad-NMs in complex matrices, using conventional analytical methods. b) Protocols to trace the evolution of Ad-NMs properties throughout their lifecycle, and methodologies for accelerated testing. c) in vitro multi-cellular models, in vivo (invertebrate) models, and ecotoxicological models for assessing the environmental and health hazard of Ad-NMs. Grouping and read-across approaches will build up on results from existing Horizon initiatives (GRACIOUS, SUNSHINE and HARMLESS), and will generate novel algorithms for similarity assessment, grouping hypotheses and Integrated Approaches to Testing and Assessments (IATAs). The protocols generated in the project will be validated through peer-reviewed publications and disseminated in Open Access. Furthermore, we will engage with the relevant standardisation bodies and organisations (OECD, ISO, CEN) to ensure that our approach can be translated into industry standards. The consortium comprises 11 European partners and 1 international partner (China), among which 4 high-tech SMEs specialised in Ad-NMs, and a high-tech incubator / accelerator. POTENTIAL contributes to the Horizon Europe workprogram by helping establish appropriate methods for cost-efficient assessment and prediction of the health and environmental effects of Ad-NMs, as well as supporting the inclusion of new methods to support safe-and-sustainable-by-design. ver más
31/12/2026
IRFMN
3M€
Duración del proyecto: 49 meses Fecha Inicio: 2022-11-24
Fecha Fin: 2026-12-31

Línea de financiación: concedida

El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-11-24
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
HORIZON-CL4-2022-DIGITAL-EMERGING-01-35: Advanced characterisation methodologies to assess and predict the health and environmental risks of nanomaterials (RIA)
Cerrada hace 2 años
Presupuesto El presupuesto total del proyecto asciende a 3M€
Líder del proyecto
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEG... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5