Phytobacterial vesiculation: regulation, cargoes and function
Phytopathogenic bacteria are of substantial economic importance, threatening the quantity and quality of food production. Reducing crop losses from disease epidemics caused by bacterial pathogens is critical for the supply of agri...
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Información proyecto PhytoBactoEVs
Duración del proyecto: 23 meses
Fecha Inicio: 2023-06-01
Fecha Fin: 2025-05-31
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Descripción del proyecto
Phytopathogenic bacteria are of substantial economic importance, threatening the quantity and quality of food production. Reducing crop losses from disease epidemics caused by bacterial pathogens is critical for the supply of agricultural produce. On the other hand, colonisation of plants with beneficial bacteria can stimulate plant growth by increasing the nutrient uptake by roots or prime plants for enhanced defense against biotic and abiotic stresses, which can help to improve (or bring new approaches to) efforts to reach sustainable agriculture.Cell-to-cell communication, which is ubiquitous in all biological systems, plays a critical role in plant-bacteria interaction. Recently it has been considered that one of the significant ways to achieve cell-to-cell communication is through extracellular vesicles (EVs). These cytosol-containing membrane spheres provide selection, storage, and protection against degradation of enclosed cargoes in a highly dynamic and environmental cue-responsive manner. EVs also offer the opportunity for directed cargo delivery to dedicated recipient cells and serve as a quick adaptation strategy to react to a changing environment [1].This project proposal aims to shed light on the vesiculation process of phytobacteria and the role of EVs in plant-bacteria interactions. The missing detailed understanding of vesiculation and EVs' properties is a critical gap in our complete knowledge of cell-to-cell communication, especially in plant-bacteria interactions.At its completion, this project will lead to new insights into the crucial tool, cell-to-cell communication, contributing to the virulence of pathogenic phytobacteria and the mechanism for how bacterial symbionts promote plant growth and fitness.