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PANBioRA

financed

Closed

Personalized And Or Generalized Integrated Biomaterial Risk Assessment

PANBioRA aims at providing a comprehensive solution for the time- and cost-effective risk assessment of i) new biomaterials under health or disease states or ii) a given biomaterial for each patient in a personalized manner. It wi... see more

31/12/2021

Steinbeis 2i GmbH

8M€

Project Budget: 8M€

Project leader

STEINBEIS 2I GMBH No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 20 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2021-12-31

NMBP-12-2017: Development of a reliable methodolo... Specific Challenge:The development of new biotechnology-based products needs to be complemented with...

I+D

Cerrada does 8 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

20 Participantes

Steinbeis 2i GmbH

499.63K€ | Leader

CHUL

405.56K€ | participant

THE UNIVERSITY OF NOTTINGHAM

736.50K€ | participant

SPARTHA MEDICAL

152.35K€ | participant

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Project duration: 48 months Date Start: 2017-12-12
End date: 2021-12-31

Project leader

STEINBEIS 2I GMBH No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 8M€

participation deadline Sin fecha límite de participación.

Project description PANBioRA aims at providing a comprehensive solution for the time- and cost-effective risk assessment of i) new biomaterials under health or disease states or ii) a given biomaterial for each patient in a personalized manner. It will standardize the evaluation of biomaterials and open the venue for pre-implantation, personalized diagnostics for biomaterial based applications. PANBioRA will provide a modular platform to assess risks at different aspects and length scales. This comprises antibody response, cytotoxicity/genotoxicity at cell level, systemic and local effects at tissue and connected tissues (organ-on-a-chip) level. Moreover, physicochemical and biomechanical characterisation as well as predictive modelling at systems level will complement the system. This will be achieved by connecting testing modules in a structure supported by web-based modelling and risk radar tools together with a biomechanical testing system. The platform will incorporate standardized protocols yielding significantly more information than the current methods for biomaterial risk assessment. Its accuracy will be demonstrated using known reference materials and validated in a pre-clinical setting. PANBioRA will for the first time, predict the patient specific response to a given biomaterial before its implantation. This measure will allow for the selection of the best suitable material, minimizing side effects and improving health outcomes. It will also accelerate the process of validation of the biocompatibility of new devices by providing an automated, comprehensive process for the parallel assessment of risks at different scales aiding new biomaterial discovery and commercialisation. Altogether, PANBioRA will lead to a substantial economic impact due to a reduction of the amount of tests, decrease in healthcare costs due to complications. It will provide the necessary tools proper risk management related to biomaterials.

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