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PIONEER

Financiado

Peri Ocularly Navigated Exteroceptive Snake Robot for Novel Retinal Intervention...

Peri Ocularly Navigated Exteroceptive Snake Robot for Novel Retinal Interventions Intraocular treatments require manipulation of structures with dimensions comparable to hand tremor. The demanded dexterity, coupled with reduced haptic and depth perception, calls for robotic assistance. Despite notable benefit... ver más

31/03/2023

KINGS COLLEGE LOND...

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

KINGS COLLEGE LONDON No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 3 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-03-31

ERC-2016-STG: ERC Starting Grant

I+D

Cerrada hace 9 años

0% 100% 100%

3 Participantes

KINGS COLLEGE LONDON

970.91K€ | Lider

LABIANA LIFE SCIENCES

414.06K€ | Participante

UNIVERSITY COLLEGE LONDON

529.09K€ | Participante

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Duración del proyecto: 72 meses Fecha Inicio: 2017-03-15
Fecha Fin: 2023-03-31

Líder del proyecto

KINGS COLLEGE LONDON No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Descripción del proyecto Intraocular treatments require manipulation of structures with dimensions comparable to hand tremor. The demanded dexterity, coupled with reduced haptic and depth perception, calls for robotic assistance. Despite notable benefits, existing robots are not clinically disruptive but follow well-trodden intervention protocols with significant limitations, e.g. lack of flexibility at the scleral incision and limited manipulation bandwidth, as to avoid scleral, lens, and retinal damage. Robotics also does not obviate the prerequisite of the risky, cataract-inducing vitrectomy, which may cause retinal detachment (RD) or sight loss. Novel interventions like stem-cell delivery pose yet further challenges. Apart from removing healthy vitreous, they require millimetre-long retinal tears, lifting the retinal membrane, and injecting a stem-cell suspension or sheet. Current robots facilitate manipulations but conceivably neither enable alternative approaches nor reduce retinal-tear-induced risks. PIONEER, the proposed snake robot, can disrupt clinical protocol by navigating peri-ocularly and around the orbital muscles to suprachoroidally reach the retina. Revolutionizing existing robot paradigms, PIONEER innovates both scientifically and technically. Optimal robot compliance will ensure force-adaptive peri-ocular steering conforming to the eye’s exterior. A tactile sleeve with micro-sensors will provide exteroceptive force sensing and shape estimation. Enhanced navigation, fusing optical coherence tomography with on-line vessel detection from novel tip-mounted probes, will ensure safe guidance to avoid vessels through imposed virtual fixtures and path planning. No vitrectomy will be required and the posterior scleral incision will leave the retinal membrane intact, minimising RD risk. PIONEER can be an enabler of emerging stem-cell interventions and futuristic procedures like drug-implant insertion and nerve interfacing, currently at human-dexterity limits or impossible.

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