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PARAFLUO

Financiado

Cerrado

Parallel fluorescence spectroscopy tools for micro and nano analytical applicati...

Parallel fluorescence spectroscopy tools for micro and nano analytical applications down to single biomolecules Analytical methods based on fluorescence measurements are widely employed for investigating biological process at cellular level. A modern technique is fluorescence-lifetime imaging microscopy (FLIM), where a map is obtained of th... ver más

31/08/2011

MPD

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

MICRO PHOTON DEVICES SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 8 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2011-08-31 No tenemos la información de la convocatoria

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

8 Participantes

MPD

0.00€ | Lider

HWU

N.D. | Participante

POLIMI

N.D. | Participante

HPL

N.D. | Participante

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Líder del proyecto

MICRO PHOTON DEVICES SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Analytical methods based on fluorescence measurements are widely employed for investigating biological process at cellular level. A modern technique is fluorescence-lifetime imaging microscopy (FLIM), where a map is obtained of the fluorescent emission lifetime versus position in a cell. The objective of project PARAFLUO is an innovative instrumentation system that will enhance and extend the usefulness of FLIM, making possible to obtain simultaneously FLIM data separately for the various spectral components of the emission. There is wide consensus among experimenters that this spectrally resolved technique (called sFLIM) will support a better understanding of the biological processes involved. Such understanding is paramount for the (patho)physiology of tissues and organisms and gives a base for gaining a better insight in key medical issues, such as the origin and growth mechanisms of tumors. The optoelectronic instrumentation developed will be useful also for other market objectives, such as simultaneous multi-spectral profiling of objects by laser detection and ranging (LADAR) techniques. The developments envisaged are essentially: (a) a photon-counting array detector based on the silicon single-photon avalanche diode (SPAD) technology; (b) a new micro-lens system for focusing light onto the detector and (c) an ASIC based multichannel time correlated single photon counting (TCSPC) system, integrated with an optoelectronic setup in a confocal microscope. The base of the PARAFLUO consortium is given by three SME’s; each one having a consolidated technical know-how and an active presence in the market over one of the quoted scientific-technical (S/T) areas. Five RTD performers have been selected primarily because of their high international standard in these areas; furthermore, each of them has experience of active collaboration with the SME directly concerned by the specific S/T work. A professional partner supports the coordinator and ensures timely and efficient exchange of materials and information in the project.

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