Innovating Works

OSIRIS

Financiado
Organic Semiconductors Interfaced with Biological Environments
Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structur... Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic devices. Proof-of-concept of versatile applications has been demonstrated – sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit Stark shifts related to interfacial fields, determine nanoscale charge mobility using terahertz spectroscopy in attenuated total reflection geometry, and simultaneously measure ionic transport. ver más
31/07/2022
1M€
Duración del proyecto: 69 meses Fecha Inicio: 2016-10-26
Fecha Fin: 2022-07-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2022-07-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2016-STG: ERC Starting Grant
Cerrada hace 9 años
Presupuesto El presupuesto total del proyecto asciende a 1M€
Líder del proyecto
UNIVERSITAET BERN No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5