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OSIRIS

financed

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Organic Semiconductors Interfaced with Biological Environments

Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structur... see more

31/07/2022

UNIVERSITAET BERN

1M€

Project Budget: 1M€

Project leader

UNIVERSITAET BERN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

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Financing granted El organismo H2020 notifico la concesión del proyecto The day 2022-07-31

ERC-2016-STG: ERC Starting Grant Scope:Objectives

I+D

Cerrada does 9 years

0% 100% 100%

characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

3 Participantes

UNIVERSITAET BERN

1.50M€ | Leader

REVERTE PRODUCTOS MINERALES

539.24K€ | participant

UNIFR

N.D. | participant

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Project duration: 69 months Date Start: 2016-10-26
End date: 2022-07-31

Project leader

UNIVERSITAET BERN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 1M€

participation deadline Sin fecha límite de participación.

Project description Transducing information to and from biological environments is essential for bioresearch, neuroscience and healthcare. There has been recent focus on using organic semiconductors to interface the living world, since their structural similarity to bio-macromolecules strongly favours their biological integration. Either water-soluble conjugated polyelectrolytes are dissolved in the biological medium, or solid-state organic thin films are incorporated into bioelectronic devices. Proof-of-concept of versatile applications has been demonstrated – sensing, neural stimulation, transduction of brain activity, and photo-stimulation of cells. However, progress in the organic biosensing and bioelectronics field is limited by poor understanding of the underlying fundamental working principles. Given the complexity of the disordered, hybrid solid-liquid systems of interest, gaining mechanistic knowledge presents a considerable scientific challenge. The objective of OSIRIS is to overcome this challenge with a high-end spectroscopic approach, at present essentially missing from the field. We will address: 1) The nature of the interface at molecular and macroscopic level (assembly of polyelectrolytes with bio-molecules, interfacial properties of immersed organic thin films). 2) How the optoelectronics of organic semiconductors are affected upon exposure to aqueous environments containing electrolytes, biomolecules and cells. 3) How information is transduced across the interface (optical signals, thermal effects, charge transfer, electric fields, interplay of electronic/ionic transport). Via spectroscopy, we will target relevant optoelectronic processes with ultrafast time-resolution, structurally characterize the solid-liquid interface using non-linear sum-frequency generation, exploit Stark shifts related to interfacial fields, determine nanoscale charge mobility using terahertz spectroscopy in attenuated total reflection geometry, and simultaneously measure ionic transport.

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