Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

OPTIC-TB

Financiado

OPTIMIZING THE IMPLEMENTATION AND SCALE-UP OF THE WHO TB TREATMENT DECISION ALGO...

OPTIMIZING THE IMPLEMENTATION AND SCALE-UP OF THE WHO TB TREATMENT DECISION ALGORITHMS FOR CHILDREN WITH PULMONARY TUBERCULOSIS IN SUB-SAHARAN AFRICA Every year, about a million children under 15 years are diagnosed with Tuberculosis (TB) worldwide, and about a quarter die. However, over 60% of children with TB remain undiagnosed, particularly in sub-Saharan Africa, which accou... ver más

31/03/2028

HVL

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

HOGSKULEN PA VESTLANDET No se ha especificado una descripción o un objeto social para esta compañía.

Ver 7 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-03-07

HORIZON-JU-GH-EDCTP3-2023-01-03: Implementation research/real life a... ExpectedOutcome:This topic aims at supporting activities that contribute to one or several of the ex...

I+D

Cerrada hace 1 año

0% 100% 100%

7 Participantes

HVL

705.28K€ | Lider

KAMPALA INTERNATIONAL UNIVER...

MAKERERE UNIVERSITY LUNG INS...

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

FIND-TB Development and Validation of ‘findtb’, A Novel Digital Tool... 2M€ Cerrado

BES-2014-071066 TRANSFORMANDO LAS NUEVAS TECNOLOGIAS DE SECUENCIACION EN UNA... Cerrado

SAF2013-43521-R TRANSFORMANDO LAS NUEVAS TECNOLOGIAS DE SECUENCIACION EN UNA... Cerrado

PROTID Randomised Controlled Trial of Preventive Treatment of Laten... 2M€ Cerrado

FJC2021-047271-I Paediatric TB: new diagnostic approaches 65K€ Cerrado

SAF2016-77346-R TUBERCULOSIS MULTIRRESISTENTE: DE LA BIOLOGIA AL DIAGNOSTICO 242K€ Cerrado

Duración del proyecto: 48 meses Fecha Inicio: 2024-03-07
Fecha Fin: 2028-03-31

Líder del proyecto

HOGSKULEN PA VESTLANDET No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 4M€

Descripción del proyecto Every year, about a million children under 15 years are diagnosed with Tuberculosis (TB) worldwide, and about a quarter die. However, over 60% of children with TB remain undiagnosed, particularly in sub-Saharan Africa, which accounts for about 20% of the global burden of paediatric TB cases. In 2022, WHO issued an interim general recommendation to use integrated Treatment-Decision Algorithms (TDAs) to diagnose TB in children under 10 years. However, this recommendation was based on very low certainty of evidence. Therefore, we are seeking funding to address four objectives: 1) To compare the effectiveness of TDAs and the Standard of Care in routine clinical settings 2) To identify processes and contextual factors that influence the effectiveness and fidelity in the implementation of TDAs 3) To compare the costs, cost-effectiveness, and the population level impact of the TDA strategies on the burden of TB and 4) To validate the diagnostic performance (sensitivity, specificity, negative and positive predictive values) of the TDAs in various health system settings and clinical context. A four-year pragmatic open-label cluster randomized controlled trial will be conducted in 120 primary health facilities in Tanzania, Uganda, and DR Congo. The primary outcome is the proportion of children detected and initiated on TB treatment. About 60,000 children with presumptive TB will be screened. We anticipate that this project will yield results that address the issue of low detection rates of paediatric TB in sub-Saharan Africa and beyond, build research capacity in conducting implementation research in low-income countries, and foster networking and collaboration between the partner institutions.

Conecta tu I+D

Entra hoy

¿Olvide mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores