Innovating Works

1-SWITCH

Financiado
One step switchable fluorescent probe assay for direct virus detection.
Since March 2020, the world is facing the Covid-19 pandemic. As of September 2020, over 900 000 people have died of the disease, caused by the SARS-CoV-2 virus. The WHO recommendations in order to limit the spread of the virus are... Since March 2020, the world is facing the Covid-19 pandemic. As of September 2020, over 900 000 people have died of the disease, caused by the SARS-CoV-2 virus. The WHO recommendations in order to limit the spread of the virus are to test, trace and isolate. To be successful, this strategy requires fast and massive testing. Today, tests are performed using PCR, a resource-intensive process requiring extraction of the viral RNA before nucleic acid amplification. PCR tests are slow (several hours) and require an army of advanced laboratory equipment or automated diagnostic workflow setups for the various steps, and thus prevalent in centralized facilities testing samples in large batches. Consequently, the turn-around time for these tests has proven to be 24-48 hours globally. Here, we propose to develop a new Covid-19 test, 1-SWITCH, consisting of a single step switchable fluorescent probe assay. The 1-SWITCH technology will use low cost reagents, and therefore will be cheaper than current available Covid-19 tests. The sensitivity of the test will be superior to the one of antigen tests and comparable to the one of PCR tests. This 1-step, 1-tube method will detect the virus directly within minutes and eliminates the assay complexity, thus facilitating smoother workflows in laboratory diagnostics as well as point of care screening. This will consist of a major breakthrough in clinical diagnostics. Plans for bringing our research finding to a commercial innovation are presented. ver más
31/10/2022
LUNDS UNIVERSITET
150K€
Duración del proyecto: 18 meses Fecha Inicio: 2021-04-16
Fecha Fin: 2022-10-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2022-10-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2020-POC: Call for proposals for ERC Proof of Concept Grant
Cerrada hace 4 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
LUNDS UNIVERSITET No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5