Innovating Works

OLIGOMED

Financiado
Oligonucleotides for Medical Applications
The use of synthetic oligonucleotides (ONs, short DNA or RNA strands) in the treatment of genetic diseases is a rapidly growing field, and the most promising alternative to gene therapy or small molecules. Most pharmaceutical comp... The use of synthetic oligonucleotides (ONs, short DNA or RNA strands) in the treatment of genetic diseases is a rapidly growing field, and the most promising alternative to gene therapy or small molecules. Most pharmaceutical companies shift from in-house platform development to product-specific licensing and co-development to get ON based therapies past clinical trials. Therefore there is a growing and currently unmet need for a combined academic and industry-based multidisciplinary research to further advance the field by bringing together the separated and fragmented R&D efforts of diverse ON technologies. OLIGOMED will address these needs by: - uniting world-class academic and private sector expertise in ON chemistry, bio-analysis and medical applications - developing a next generation ON platform technology based on combining tailored synthetic ONs with smart delivery - optimising ON therapies through testing in medicinal environments We will use these novel ON technologies to develop innovative treatment options for high-impact genetic diseases, i.e. Huntington’s disease, cardiovascular diseases and cancer. Our European intersectoral and multidisciplinary research and training network for 15 Early Stage Researchers (ESRs) will deliver: -highly skilled scientific staff required to fully exploit ON therapeutics for personalised medicine -top-class training in organic and chemoenzymatic synthesis, ON analysis, and biomedical/medicinal testing -transferable skills courses, specific industry relevant workshops and public engagement activities This combination makes OLIGOMED a truly exciting programme for ESRs. The platform will immediately benefit to both European citizens and commercial partners. In the long term, OLIGOMED`s flexible platform technology will be taken forward by our private sector and research institutions for exploitation and will thus strengthen the European innovation capacity in the field of ON therapies. ver más
30/06/2025
SOUTHAMPTON
4M€
Duración del proyecto: 58 meses Fecha Inicio: 2020-08-13
Fecha Fin: 2025-06-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2020-08-13
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
MSCA-ITN-2020: Innovative Training Networks
Cerrada hace 4 años
Presupuesto El presupuesto total del proyecto asciende a 4M€
Líder del proyecto
UNIVERSITY OF SOUTHAMPTON No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5