Innovating Works

NormNets

Financiado
Normalization of Multimodal Brain Networks for Integral and Predictive Mapping o...
Normalization of Multimodal Brain Networks for Integral and Predictive Mapping of Neurological Disorders Modern network science has introduced exciting new opportunities for understanding the brain as a complex system of interacting units in both health and disease and across the human lifespan. Despite the rapidly growing interdisci... Modern network science has introduced exciting new opportunities for understanding the brain as a complex system of interacting units in both health and disease and across the human lifespan. Despite the rapidly growing interdisciplinary science of complex networks, which spans the range from genetic and metabolic networks all the way up to social and economic systems, it remains a formidable challenge to identify the most representative and shared brain alterations caused by a specific disorder (e.g., Alzheimer’s disease), namely ‘disorder signature’, in a population of brain networks, let alone multi-modal brain networks where each brain network is derived from a particular neuroimaging modality (e.g., functional or diffusion magnetic resonance imaging (fMRI or dMRI)). Such integral signature can be revealed by what I name as a multimodal connectional brain template (CBT), which would constitute an unprecedented contribution to network neuroscience, rooted in firstly learning brain connectivity normalization and secondly foreseeing its evolution. During this fellowship, I will develop NormNets, a novel technique leveraging the power of geometric deep-learning to meet this challenge by normalizing a population of multimodal brain networks. Particularly, NormNets tools will substantially advance the field of network neuroscience by estimating not only an integral but also a predictive mapping of neurological disorders. In addition to the multi-disciplinary high-quality training I will receive at both host and secondment institutions, this fellowship will remarkably consolidate and accelerate my career on the international landscape scene in the new cross-disciplinary area of geometric deep learning & integration connectomics I will pioneer during this fellowship. With the endorsement of international multi-sectoral stakeholders, open NormNets resources will impact on and contribute towards the development of connectomics-rooted predictive precision medicine. ver más
31/03/2022
ITU
145K€
Duración del proyecto: 24 meses Fecha Inicio: 2020-03-20
Fecha Fin: 2022-03-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2022-03-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
WF-02-2019: Widening Fellowships
Cerrada hace 5 años
Presupuesto El presupuesto total del proyecto asciende a 145K€
Líder del proyecto
ISTANBUL TEKNIK UNIVERSITESI No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5