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NELLAFLOW

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New generation of low cost Lateral Flow Assays LFAs coupled with paper based e...

New generation of low cost Lateral Flow Assays LFAs coupled with paper based electrical gas sensors An application study for the rapid determination of Salmonella in food Over 420,000 people die each year due to contaminated foodstuffs, with Salmonella identified as one of the key global causes. Yet conventional methods for the determination of Salmonella in food require several enrichment and subc... ver más

31/01/2025

IMPERIAL COLLEGE O...

319K€

Presupuesto del proyecto: 319K€

Líder del proyecto

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND ME... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2025-01-31

MSCA-IF-2020: Individual Fellowships

I+D

Cerrada hace 4 años

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1 Participantes

IMPERIAL COLLEGE OF SCIENCE...

319.40K€ | Lider

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Duración del proyecto: 45 meses Fecha Inicio: 2021-04-14
Fecha Fin: 2025-01-31

Líder del proyecto

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND ME... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 319K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Over 420,000 people die each year due to contaminated foodstuffs, with Salmonella identified as one of the key global causes. Yet conventional methods for the determination of Salmonella in food require several enrichment and subculture steps performed by trained staff at lab-based facilities, taking up to 5 days to obtain a result. Lateral Flow Assays (LFAs) have emerged as a powerful alternative method for Salmonella testing because they are rapid, simple-to-use and amenable for Point-of-Need (PoN). However, current LFAs available in the market only provide binary (yes/no) or semiquantitative responses, lacking the rapidness and sensitivity required for food monitoring due to the limitations of the colorimetric transduction. By the integration of paper-based electrical gas sensors (PEGS) as detectors into Lateral Flow Assays, NELLAFLOW will address the challenge of quantitative determination of Salmonella in food without the requirement of long enrichment steps. PEGS have already proven to be highly sensitive towards water-soluble gases determination. They exploit the intrinsic hygroscopic characteristics of cellulose paper and the changes in its ionic conductance in the presence of water-soluble gases. The incorporation of aptamers as biological recognition elements in the PEGS-LFA platform will improve the implementation of the prototype for on-site monitoring as they are low-cost, highly specific, and stable at room temperature. Through a multidisciplinary approach (biomolecular engineering, analytical chemistry, printed electronics, microbiology) NELLAFLOW will tackle a problem in the food industry with an innovative versatile technology that can be easily transferred to other application fields. By combining academic and non-academic training, NELLAFLOW will broaden the Fellow expertise through new technical and management skills that will complement her previous experience while delivering high impact results and transfer of knowledge.

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