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NeuroCare

Financiado

Cerrado

Neuronal NanoCarbon Interfacing Structures

NeuroCare aims to create better retinal, cortical and cochlear implantable devices through the use of improved interfacing between the electronic implants and living cells. The NeuroCare concept involves low-cost, carbon-based mat... ver más

28/02/2015

CEA

5M€

Presupuesto del proyecto: 5M€

Líder del proyecto

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 12 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2015-02-28 No tenemos la información de la convocatoria

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Información adicional privada

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12 Participantes

CEA

0.00€ | Lider

UNIVERSITY COLLEGE LONDON

CNRS

N.D. | Participante

TUM

N.D. | Participante

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Líder del proyecto

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 5M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto NeuroCare aims to create better retinal, cortical and cochlear implantable devices through the use of improved interfacing between the electronic implants and living cells. The NeuroCare concept involves low-cost, carbon-based materials, well-adapted for medical implants, because they (i) offer wide range of electronic properties (metal, semiconductor and insulator), (ii) are bio-inert and (iii) are physically robust. Coupling between electronic devices and neurons was recently studied using soft, nanocrystalline diamond-based micro-electrode arrays, evaluated in laboratory animals for retinal stimulation. These diamond implants considerably reduced gliosis, enabled stimulation currents to be raised by more than one order of magnitude before causing visible chemical alteration, and enabled long lasting operation with reduced biofouling. Our previous experience with nanocrystalline diamond will be directly built upon through the introduction of atomic layers of graphene to diamond surfaces. NeuroCare will specifically focus on: • Carbon-biointerface development offering reduced biofouling over the state-of-the-art, as set by the DREAMS project and improved biocompatibility • Interfacing of rigid MEAs and FETs with cells and organs to improve bidirectional communication with neurons for in vitro research and pharmacological applications • Nanoscale surface engineering and flexible macroscale implant materials for optimal contact to biological tissue • Making and testing implantable MEAs and FETs for complex multichannel neuronal communication - targeting the specificity in vivo of the implantable devices for 3 high-impact clinical applications Neurocare partners will test interfaceable and implantable devices via in vitro and in vivo testing. NeuroCare federates 12 partners: CEA (LIST and CLINATEC), Ecole Supérieure d'Ingénieurs en Electronique, Forschungszentrum Jülich, Ayanda Biosystems SA, University College London (London Centre for Nanotechnology), Johannes

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