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COGBIAS

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Neural circuitry and health consequences of cognitive bias

Stress has long been a major concern among researchers interested in health and welfare. Most of their work has considered stress from either a biological or an environmental perspective, focusing on the activation of the physiolo... ver más

31/01/2022

FUNDACAO CALOUSTE...

271K€

Presupuesto del proyecto: 271K€

Líder del proyecto

FUNDACAO CALOUSTE GULBENKIAN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-01-31

MSCA-IF-2017: Individual Fellowships

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Cerrada hace 7 años

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3 Participantes

FUNDACAO CALOUSTE GULBENKIAN

270.86K€ | Lider

INTER-UNIVERSITY RESEARCH IN...

ROIS

N.D. | Participante

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Duración del proyecto: 46 meses Fecha Inicio: 2018-03-28
Fecha Fin: 2022-01-31

Líder del proyecto

FUNDACAO CALOUSTE GULBENKIAN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 271K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Stress has long been a major concern among researchers interested in health and welfare. Most of their work has considered stress from either a biological or an environmental perspective, focusing on the activation of the physiological systems involved in the stress process or the role of stressful life events in specific diseases. While interesting, if we are to fully understand the effects of stress on health, we must also take into account a psychological perspective that considers an individual’s perception of stress. Indeed, a deep understanding of the neural circuitry underlying psychological stress and its physiological consequences is crucial to meaningfully explain inter-individual variations in vulneraibility to stress. In this way, my ongoing research has revealed some preliminary results which indicate ‒ for the first time ‒ that cognitive bias towards pessimistic judgments (i.e. some individuals consistently evaluate ambiguous stimuli as negative) may predict an individual’s susceptibility to the detrimental effects of chronic stress. These groundbreaking results shed light on a completely unexplored and highly promising avenue of research, based on the potential impact of evaluation biases regarding stress on an individual’s vulnerability to stress-associated diseases. In this framework, COGBIAS firstly aims to characterise the specific neural circuits underlying cognitive bias by which stress is perceived, processed, and transduced into a neuroendocrine response, using zebrafish (Danio rerio) as a model. Secondly, COGBIAS aims to unravel the role of subjective stress on resilience to stress-associated diseases. Hence, the multidisciplinary and unique perspective of this project, combining behavioural, neural, genetic, and physiological sciences, has the potential to reinforce the already European competitiveness in the area of stress-related health and management.

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