NaTOS: Nanoscale Thermo Optical Sensing is the concept of a new truly label free bio-sensor device capable of monitoring transient molecular interactions. The sensor utilizes plasmonic gold nanorods (NR) as both nanoscale heating...
ver más
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Proyectos interesantes
FIS2014-52212-R
NANOBIOESPECTROSCOPIA (RAMAN Y FLUORESCENCIA): NANOSISTEMAS...
121K€
Cerrado
MultiSense
Nanoplasmonic sensing of multi molecular protein interaction...
2M€
Cerrado
FIS2017-84318-R
NANOSISTEMAS BASADOS EN EFFECTOS PLASMONICOS ORIENTADOS HACI...
109K€
Cerrado
PID2020-117779RB-I00
DISEÑO DE NANOESTRUCTURAS PLASMONICAS QUIRALES PARA TERANOST...
382K€
Cerrado
PLASMAQUO
Development of plasmonic quorum sensors for understanding ba...
2M€
Cerrado
Duración del proyecto: 24 meses
Fecha Inicio: 2018-02-26
Fecha Fin: 2020-02-29
Líder del proyecto
UNIVERSITEIT LEIDEN
No se ha especificado una descripción o un objeto social para esta compañía.
TRL
4-5
Presupuesto del proyecto
166K€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
NaTOS: Nanoscale Thermo Optical Sensing is the concept of a new truly label free bio-sensor device capable of monitoring transient molecular interactions. The sensor utilizes plasmonic gold nanorods (NR) as both nanoscale heating source and optical near field sensor. Proteins and enzymes will be monitored as they change the intensity scattered by a single NR as they diffuse through the nanorod's nearfield.
The simultaneous laser induced and thus tunable heating of the NR will induces a nanoscale temperature gradient that allows to probe the analytes with respect to their thermophoretic behavior. This analyte specific behavior provides specific thermophortic fingerprints which will be used to identify and distinguish between different proteins and in further extend also to monitor the interaction between different species of analytes.
This novel type of sensor does not require fluorescent labels nor does it rely on tethering of specific receptors and the consequent binding of analytes to the NRs. In contrast to current state of the art techniques this truly label-free sensor does not suffer from binding induced life time restrictions and can obtain statistical significant datasets without the requirement, but with the possibility of multiplexing.