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mtFOIE GRAS

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mitoFOIE GRAS Non invasive Profiling of Mitochondrial Function in Non Alcoholic...

mitoFOIE GRAS Non invasive Profiling of Mitochondrial Function in Non Alcoholic Fatty Liver Disease "Non-Alcoholic Fatty Liver Disease (NAFLD), including its more pathologic consequence, non-alcoholic steatohepatitis (NASH), is believed to be the most common chronic liver disease worldwide, affecting between 6 to 37% of the popu... ver más

31/08/2022

CNC

455K€

Presupuesto del proyecto: 455K€

Líder del proyecto

CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASS... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 14 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-08-31

MSCA-RISE-2016: Research and Innovation Staff Excha...

I+D

Cerrada hace 8 años

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No hay información privada compartida para este proyecto. Habla con el coordinador.

14 Participantes

CNC

126.00K€ | Lider

PLASTICOS HITA

235.89K€ | Participante

UNIBA

67.50K€ | Participante

FFUL

18.00K€ | Participante

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Duración del proyecto: 68 meses Fecha Inicio: 2016-12-05
Fecha Fin: 2022-08-31

Líder del proyecto

CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASS... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 455K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto "Non-Alcoholic Fatty Liver Disease (NAFLD), including its more pathologic consequence, non-alcoholic steatohepatitis (NASH), is believed to be the most common chronic liver disease worldwide, affecting between 6 to 37% of the population. NAFLD is a so called ‘silent killer’, as clinical symptoms only surface at late stages of the disease, when it is no longer treatable: untreated, NAFLD/NASH can lead to cirrhosis and hepatocellular carcinoma, culminating in liver failure. Currently the best method of diagnosing and staging the disease is liver biopsy, a costly, invasive and somewhat risky procedure, not to mention unfit for routine assessment. Besides, no therapeutic consensus exists for NAFLD/NASH treatment. mtFOIE GRAS (Foie Gras being French for ""fat liver"") proposes to address the pressing need for non-invasive, accurate, rapid assessment of NAFLD/NASH stages, before and after intervention, through the development of biomarkers and innovative tools to follow mitochondrial (mt) dysfunction, a central mediator of fatty liver disease pathogenesis. This promising R&D strategy will also bring new knowledge about the disease mechanisms and improved understanding of the pathogenic process and disease drivers. To that end, mtFOIE GRAS envisages a training-through-work plan that brings together an intersectoral, multidisciplinary team of researchers and technicians experts in their fields, from basic to translational research, clinical practice, technology commercialization and public advocacy. Together with several PhD students, the team will share expertises and work synergistically along the value creation chain to address the unmet medical need of more informative NAFLD assessment. In the process, mtFOIE GRAS will endow the involved staff with excellent scientific knowledge and transferable skills while building and strengthening intersectoral cooperation among partners, thus contributing to EU RD&I excellence."

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