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uBeat

Financiado

Mimic human complexity in a Beat to revolutionize the drug development

BiomimX Beating organs-on-chips (OoC) are in vitro miniaturized and living replica of human organs and diseases, building upon cutting-edge technologies and human cells. Beating OoC provide a faithful replication of native human p... ver más

30/11/2022

BiomimX

75K€

Presupuesto del proyecto: 75K€

Líder del proyecto

BIOMIMX SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-11-30

HORIZON-EIE-2021-SCALEUP-01-03: Women TechEU ExpectedOutcome:

Innovación

Cerrada hace 3 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

BiomimX

75.00K€ | Lider

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Duración del proyecto: 6 meses Fecha Inicio: 2022-05-16
Fecha Fin: 2022-11-30

Líder del proyecto

BIOMIMX SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 75K€

Descripción del proyecto BiomimX Beating organs-on-chips (OoC) are in vitro miniaturized and living replica of human organs and diseases, building upon cutting-edge technologies and human cells. Beating OoC provide a faithful replication of native human physiology integrating miniaturized 3D cell culture techniques, mechanical stimulation (uBeat®) and electrical recording capabilities (uSense). BiomimX’s proprietary key technology (uBeat®) supports 3D human cell cultures and integrates a controlled and tunable mechanical stimulation system. uBeat® leads to the generation of mature and functional miniaturized replication of human organs adequate to test compounds toxicity/functionality in a high-throughput fashion. Integration of uSense allows real-time evaluation of clinically relevant parameters from the established beating models. BiomimX’s Beating OoC represent a safer, more efficient and faster alternative to poorly predictable preclinical models to date available in the drug discovery pipeline (DDP). BiomimX already demonstrated the validity of its Beating OoC models in two critical fields of the drug discovery pipeline: uHeart (human beating heart-on-chip) has been applied as early predictor of drug functional cardiotoxicity, uKnee (first in vitro model of human OA) has shown its predictive potential for the discovery of new targets for an unmet pathology. Also thanks to the contribution of Women TechEU programme, BiomimX aims at demonstrating the unprecedented potential of its disruptive innovation in reshaping the market of drug development, by i) boosting technological aspects (i.e. through an intensive industrialization process of BiomimX patented technologies) and ii) proving the versatility of its innovation and its capacity to adapt to a manifold of indications and market spaces. In line with the 3R principle, BiomimX final vision is to reduce and eventually replace animal experimentations within the next 15 years.

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