Microsphere Based Cellular Manipulation From Protein Delivery to Intracellular...
Microsphere Based Cellular Manipulation From Protein Delivery to Intracellular Palladium Catalysis
The broad aims of this research project are the application, exploitation and development of a generic microsphere cellular delivery system that will allow the delivery of a broad range of cargos into cells. This microspehere base...
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Descripción del proyecto
The broad aims of this research project are the application, exploitation and development of a generic microsphere cellular delivery system that will allow the delivery of a broad range of cargos into cells. This microspehere based technology will enable the efficient deliver of benign, large nano-small micron-sized particles and their associated cargos into cells. Controlled release from these carriers of their associated cargos, into mammalian cells will allows a variety of cellular processes to be modulated and followed in real time, while providing a means of tagging and tracking cells in an in vivo environment. These microspheres have, quite remarkably, been demonstrated to allow the delivery of specific chemical reagents into cells. I will exploit the delivery of palladium based catalysts into cells to carryout a range of quite unique cell based transformations!