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miRNA-DisEASY

Financiado

Cerrado

microRNA biomarkers in an innovative biophotonic sensor kit for high specific di...

microRNA biomarkers in an innovative biophotonic sensor kit for high specific diagnosis Since 2001’s discovery of microRNAs (miRNAs) in humans, progress in genomics and transcriptomics has increased our comprehension of gene expression regulation. miRNAs are small, noncoding RNA molecules showing huge promise as clin... ver más

30/11/2019

Optoi

491K€

Presupuesto del proyecto: 491K€

Líder del proyecto

OPTOELETTRONICA ITALIA SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 8 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-11-30

MSCA-RISE-2015: Marie Skłodowska-Curie Research and...

I+D

Cerrada hace 9 años

0% 91% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

8 Participantes

Optoi

126.00K€ | Lider

UGR

27.00K€ | Participante

MHH

36.00K€ | Participante

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Duración del proyecto: 48 meses Fecha Inicio: 2015-11-20
Fecha Fin: 2019-11-30

Líder del proyecto

OPTOELETTRONICA ITALIA SRL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 491K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Since 2001’s discovery of microRNAs (miRNAs) in humans, progress in genomics and transcriptomics has increased our comprehension of gene expression regulation. miRNAs are small, noncoding RNA molecules showing huge promise as clinical biomarkers and diagnostic tools for illness and disease, as significant changes in their expression occur in response to pathological states. However, miRNA detection is still challenging nowadays, since costly, complex sample preparations and RNA amplifications are not yet reliable enough for clinical decision making. In this context, three innovative EU companies, Optoi Microelectronics - with microelectronic knowhow and manufacturing skills - DestiNA Genomics - with ‘error free’ chemical technology for microRNAs recognition – and GeneXplain – with bioinformatic capabilities - joined forces with four key academic research groups from the Universities of Trento (Italy), Granada (Spain), Hannover Medical School (Germany) and Santa Catarina (Brazil). All the parties combined their knowledge with respect to miRNA biomarkers with a particular focus on lung cancer, to develop a novel and reliable miRNA detection system for this disease. To this end, research collaborations will address the analysis of miRNAs specifically over-expressed in lung cancer, continuing experimental work already started in the past years, but with greater integration and focus. Existing close partnerships with healthcare institutions will be strengthened, ensuring multi-site and multi-ethnic sampling. In parallel, optimization and validation of a miRNA detection kit based on Optoi semiconductor optical detector will continue. The DestiNA patented technology for specific nucleic acid recognition will be refined to reach the integration and result reliability required for use in clinical point of care testing. The strong network created between the companies and the academic institutions will thus provide a unique scientific and technological environment to turn the research outputs into an innovative product for healthcare advance and progress.

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