Innovating Works

MET-EFFECT

Financiado
Metal complexes of a naturally inspired framework functionalized for cytotoxic a...
Metal complexes of a naturally inspired framework functionalized for cytotoxic and catalytic efficiency The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its abi... The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its ability to bridge chemical structure with a function, MET-EFFECT proposes brand new concept of novel multifunctional rhenium and iridium flavonoid complexes aimed to serve as metallodrugs and homogenous catalysts. The fusion of academic knowledge and industry-oriented perspective establishes a fruitful collaboration of an international and intersectoral profile. Well-recognized members of Consortium gains beyond the-state-of-the-art advances in bioinorganic chemistry by: a) developing novel Re and Ir complexes containing apigenin-like ligands, a natural bioactive flavone-type of molecules; b) determining the antitumor potential of newly synthesized Re(V) and Ir(III) complexes on a panel of various human cancer cell lines; c) evaluating the applicative potential of novel Re(V) complexes as homogeneous catalysts in OAT-inspired reactions (olefin epoxidation, oxoanions catalytic reduction and water oxidation). The structure and sentence of 7 work packages implemented through 37 secondments will enable the promotion of newly synthesized metal-based compounds in industrial environment for the sake of reaching their final applications. The widespread partnership creates an outstanding, R&I oriented ambient ensuring free knowledge sharing and career upgrade of the participating staff. By developing functional metal-based molecules, MET-EFFECT encompasses full human intellectual capacity capable to challenge technical, economic and environmental demands of wider society for applied but sustainable chemistry. ver más
31/12/2026
FMK
764K€
Perfil tecnológico estimado
Duración del proyecto: 50 meses Fecha Inicio: 2022-10-20
Fecha Fin: 2026-12-31

Línea de financiación: concedida

El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-10-20
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
Presupuesto El presupuesto total del proyecto asciende a 764K€
Líder del proyecto
Faculty of Media and Communications No se ha especificado una descripción o un objeto social para esta compañía.