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MET-EFFECT

Financiado

Metal complexes of a naturally inspired framework functionalized for cytotoxic a...

Metal complexes of a naturally inspired framework functionalized for cytotoxic and catalytic efficiency The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its abi... ver más

31/12/2026

FMK

764K€

Presupuesto del proyecto: 764K€

Líder del proyecto

Faculty of Media and Communications No se ha especificado una descripción o un objeto social para esta compañía.

Ver 7 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-10-20

HORIZON-MSCA-2021-SE-01-01: MSCA Staff Exchanges 2021 ExpectedOutcome:

I+D

Cerrada hace 2 años

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7 Participantes

FMK

170.20K€ | Lider

CENTIV

124.20K€ | Participante

VENUSROSES LABSOLUTIONS LTD

216.20K€ | Participante

IST ID

128.80K€ | Participante

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Duración del proyecto: 50 meses Fecha Inicio: 2022-10-20
Fecha Fin: 2026-12-31

Líder del proyecto

Faculty of Media and Communications No se ha especificado una descripción o un objeto social para esta compañía.

Presupuesto del proyecto 764K€

Descripción del proyecto The immense power of practice-oriented synthetic chemistry is demonstrated through the opportunity to design, synthesize, optimize, produce and apply a molecule of a desirable structure for a given purpose. In the light of its ability to bridge chemical structure with a function, MET-EFFECT proposes brand new concept of novel multifunctional rhenium and iridium flavonoid complexes aimed to serve as metallodrugs and homogenous catalysts. The fusion of academic knowledge and industry-oriented perspective establishes a fruitful collaboration of an international and intersectoral profile. Well-recognized members of Consortium gains beyond the-state-of-the-art advances in bioinorganic chemistry by: a) developing novel Re and Ir complexes containing apigenin-like ligands, a natural bioactive flavone-type of molecules; b) determining the antitumor potential of newly synthesized Re(V) and Ir(III) complexes on a panel of various human cancer cell lines; c) evaluating the applicative potential of novel Re(V) complexes as homogeneous catalysts in OAT-inspired reactions (olefin epoxidation, oxoanions catalytic reduction and water oxidation). The structure and sentence of 7 work packages implemented through 37 secondments will enable the promotion of newly synthesized metal-based compounds in industrial environment for the sake of reaching their final applications. The widespread partnership creates an outstanding, R&I oriented ambient ensuring free knowledge sharing and career upgrade of the participating staff. By developing functional metal-based molecules, MET-EFFECT encompasses full human intellectual capacity capable to challenge technical, economic and environmental demands of wider society for applied but sustainable chemistry.

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