Innovating Works

MUMVIP

Financiado
Metabolic Profiling of the Vaginal Microbiome for Reproductive Health
There is ever increasing evidence that the vaginal microbiome plays an important role in reproductive health. Studies have shown that dysbiotic states can culminate in bacterial vaginosis, urinary tract infections and premature bi... There is ever increasing evidence that the vaginal microbiome plays an important role in reproductive health. Studies have shown that dysbiotic states can culminate in bacterial vaginosis, urinary tract infections and premature birth. Although the microbiome is usually characterised by 16S rRNA sequencing, the methodology is time consuming and expensive. Here we describe the development of a desorption ionisation mass spectrometry (DESI-MS) based technique which characterises microbial community structures based upon metabolomic analysis. The technique has been successfully demonstrated for a range of applications and here we describe its commercial development as a diagnostic tool, firstly, for assessing the potential success rates of in vitro fertilisation treatments and, secondly, for stratifying patients at higher risk of pre-term birth. During the first 12 months of the project the technology will be assessed using a unique sample set collected as part of two longitudinal cohort studies. During the later stages a thorough market assessment will be performed to identify the addressable demand and to evaluate market competitors. It is envisioned that this information will allow an in depth business case, including our current intellectual property position, to be written, from which further funding can be obtained for the eventual creation of a spin out company. ver más
31/12/2020
IMPERIAL COLLEGE O...
150K€
Duración del proyecto: 21 meses Fecha Inicio: 2019-03-01
Fecha Fin: 2020-12-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2020-12-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-2018-PoC: ERC Proof of Concept Grant
Cerrada hace 6 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND ME... No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5