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TRANSGENE

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Medical translation in the history of modern genomics

The translation of basic biomedical research into clinical practice has become a central concern for science policy. Policies to foster translation are being applied to large amounts of genomic information available in open-access... ver más

31/03/2022

UEDIN

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

THE UNIVERSITY OF EDINBURGH No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-03-31

ERC-StG-2015: ERC Starting Grant

I+D

Cerrada hace 10 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

UEDIN

1.50M€ | Lider

LABORATORIO ANALITICO BIOCLI...

254.27K€ | Participante

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Duración del proyecto: 71 meses Fecha Inicio: 2016-04-12
Fecha Fin: 2022-03-31

Líder del proyecto

THE UNIVERSITY OF EDINBURGH No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The translation of basic biomedical research into clinical practice has become a central concern for science policy. Policies to foster translation are being applied to large amounts of genomic information available in open-access databases. This information is the result of concerted initiatives that, in the early 2000s, determined the full genetic sequence that characterises humans and other organisms. However, when the initiatives started the goal of determining the full sequence and making the resulting information available was not universally supported. My project will investigate how and why this objective of completing the sequence was adopted in preference to other models that prioritised the usability of the data. Newly available archives suggest that the yeast, human and pig genome initiatives underwent crucial changes from the mid-1980s onwards. In their early years, the priority had been rapid translation of results into the improvement of human and animal health. Consequently, sequence determination was limited to small areas of the genome for which there was an existing medical interest. However, as the initiatives progressed the systematic sequencing of the full genome prevailed over those approaches. My project will follow the development of these sidelined models that sought to use the sequences as they were produced, in order to investigate their significance for current translational research policies. I will develop a collaborative framework in which archival research will be combined with insights from social studies of science and innovation studies. By doing this, I seek to bridge the current fragmentation between history of science and other fields of science studies focused on present-day events. In my project, biomedical translation will be approached as a historical process that unfolds over time and can be investigated with a cross-disciplinary set of tools, to be commonly applied to historical, contemporary and prospective studies.

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