Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

MACE

Financiado

Cerrado

Maternal Communication with embryo

Mechanisms of interactions of embryos with their maternal environment are important biological filters limiting reproductive success, both in livestock and the human. Although several aspects of the embryo-maternal interactome hav... ver más

31/08/2012

USFD

172K€

Presupuesto del proyecto: 172K€

Líder del proyecto

THE UNIVERSITY OF SHEFFIELD No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2012-08-31 No tenemos la información de la convocatoria

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

USFD

0.00€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

SARM Endometrial and embryonic genomics searching for biomarkers... 3M€ Cerrado

ART-HEALTH Conception by artificial reproductive technologies and offsp... 2M€ Cerrado

SCME Selecting Creating and Modifying Embryos the ethics of new... 195K€ Cerrado

Alloem Maternal immune response to allogeneic embryos 192K€ Cerrado

HOST-SELECT Functional Analysis of Host Genetic Variants Biomarker Sele... 159K€ Cerrado

CGL2011-23368 IDENTIFICACION Y FUNCION DE MIRNAS IMPLICADOS EN LA DETERMIN... 200K€ Cerrado

Líder del proyecto

THE UNIVERSITY OF SHEFFIELD No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 172K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Mechanisms of interactions of embryos with their maternal environment are important biological filters limiting reproductive success, both in livestock and the human. Although several aspects of the embryo-maternal interactome have been studied, there is so far no systematic analysis of this biological module. Increasing our knowledge regarding maternal interaction with embryos will lead to creation of novel molecular markers of fertility that will help to improve the fertility of livestock population by genomic selection and thus provide unique competitive advantages to the animal breeding industry. Knowledge of the embryo-maternal interactome will facilitate novel approaches for improving the efficiency and safety of assisted reproduction techniques. Finally, this knowledge has cross-disciplinary applications in human health and is of immense importance for future public health. No systematic studies to date have been performed to allow construction of an in-silico model for the temporal sequence of events involved in maternal communication with embryos. All investigations so far have studied this interaction in isolation, without consideration of spatial or temporal components that may confer consequences for developmental potential. Early embryonic development, implantation and maintenance of pregnancy are critically dependent for intact and efficient communication between embryo and the maternal tract. The overall objective of this application is to identify the local proteomic factors produced in porcine oviduct and uterine horn in response to developing embryo. This information will be used to construct a systemic in-silico based model of oviduct and uterine horn proteomic secretome environment and changes in this milieu, due to embryo development. For this purpose, we evaluate the oviduct secretory proteomic profile alteration in response to embryos at different stage of development.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores