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MAST4HEALTH

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Mastiha treatment for healthy obese with NAFLD diagnosis MAST4HEALTH .

MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations a... see more

29/02/2020

HAROKOPIO UNIVERSI...

2M€

Project Budget: 2M€

Project leader

CHAROKOPEIO PANEPISTIMIO No se ha especificado una descripción o un objeto social para esta compañía.

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 16 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2020-02-29

MSCA-RISE-2015: Marie Skłodowska-Curie Research and... Scope:Objective:

I+D

Cerrada does 10 years

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characteristics of the participant

Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Private Information

No hay información privada compartida para este proyecto. Habla con el coordinador.

16 Participantes

HAROKOPIO UNIVERSITY OF ATHE...

441.00K€ | Leader

QMUL

162.00K€ | participant

MFUNS UNIVERSITY OF NOVI SAD...

108.00K€ | participant

PERSPECTUM LTD

157.50K€ | participant

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Project duration: 50 months Date Start: 2015-12-16
End date: 2020-02-29

Project leader

CHAROKOPEIO PANEPISTIMIO No se ha especificado una descripción o un objeto social para esta compañía.

Project Budget 2M€

participation deadline Sin fecha límite de participación.

Project description MAST4HEALTH is set on the concept of a multidisciplinary approach to assess a non-pharmacological intervention for managing NAFLD/NASH, one of the most common complications of obesity and diabetes mellitus in Western populations affecting approximately 50% of diabetics and 76% of obese patients. Because of limitations in current NAFLD treatment therapies, many new efforts focus on exploring non-pharmacologic means for managing the disease and in particular through dietary substances or bioactive phytochemicals in fruits, vegetables, and plants or their products. MAST4HEALTH aims at exploring the effect of Mastiha, a natural product of Greece which was recently shown to possess antioxidant/anti-inflammatory and lipid lowering properties. We designed a multicenter randomized double blind placebo controlled (parallel arm) clinical trial to test the effectiveness of Mastiha supplement as new non-pharmacologic strategy for NAFLD/NASH treatment. MAST4HEALTH will explore gene-diet interactions, more specifically the potential personalized activity of the Mastiha, and correlate genetic and epigenetic markers with metabolomic and intestinal microbiota profiles pre- and post-intervention. The effectiveness of the proposed intervention will be evaluated via clinical and laboratory markers of the disease. To this end, MAST4HEALTH will train a number of researchers and PhD students in multidisciplinary approaches of this survey. MAST4HEALTH is expected to build and enhance cooperation among partners meanwhile strengthening the interaction between our academic and non-academic sectors

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